CIUSSS Capitale nationale logo

New hope to slow down Lou Gehrig's disease - Jean-Pierre Julien's research featured on Quebec's Chief Scientist website

Read an article about research by Jean-Pierre Julien on Québec's Chief Scientist website:

It was found that 98% of ALS patients have aggregated TDP-43 protein in their cytoplasm—the substance that surrounds the nuclei of their nerve cells. These aggregates are responsible for the sufferer’s loss of function over time. The researchers relied on a virus to carry tiny synthesized antibodies into the cells to erode the protein. As a result, the cognitive and motor function of the mice improved.

This research could lead to human clinical trials within 2 to 3 years, and offers a hope of stopping the progression of the disease when a patient is diagnosed.

Read the full article here:

http://www.scientifique-en-chef.gouv.qc.ca/en/impacts-of-research-cat/nouvel-espoir-pour-ralentir-la-maladie-de-lou-gehrig/

Funding / Support / Partners

logo FRQ-S logo ctrn logo fci logo cihr irsc logo nserc logo MESISentinelle nord