Publications
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Filters: Author is Nestler, Eric J [Clear All Filters]
Biology and Bias in Cell Type-Specific RNAseq of Nucleus Accumbens Medium Spiny Neurons. Sci Rep. 2019;9(1):8350.
Gadd45b mediates depressive-like role through DNA demethylation. Sci Rep. 2019;9(1):4615.
Multidimensional Predictors of Susceptibility and Resilience to Social Defeat Stress. Biol Psychiatry. 2019;86(6):483-491.
Stress resilience is promoted by a Zfp189-driven transcriptional network in prefrontal cortex. Nat Neurosci. 2019;22(9):1413-1423.
VGF and its C-terminal peptide TLQP-62 in ventromedial prefrontal cortex regulate depression-related behaviors and the response to ketamine. Neuropsychopharmacology. 2019;44(5):971-981.
Cell-Type-Specific Role of ΔFosB in Nucleus Accumbens In Modulating Intermale Aggression. J Neurosci. 2018;38(26):5913-5924.
Corrigendum: Sex-specific transcriptional signatures in human depression. Nat Med. 2018;24(4):525.
Estrogen receptor α drives pro-resilient transcription in mouse models of depression. Nat Commun. 2018;9(1):1116.
Cocaine-Induced Chromatin Modifications Associate With Increased Expression and Three-Dimensional Looping of Auts2. Biol Psychiatry. 2017.
Establishment of a repeated social defeat stress model in female mice. Sci Rep. 2017;7(1):12838.
Ketamine and Imipramine Reverse Transcriptional Signatures of Susceptibility and Induce Resilience-Specific Gene Expression Profiles. Biol Psychiatry. 2017;81(4):285-295.
The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain. Nat Genet. 2017;49(8):1239-1250.
MicroRNAs 146a/b-5 and 425-3p and 24-3p are markers of antidepressant response and regulate MAPK/Wnt-system genes. Nat Commun. 2017;8:15497.
Sex-specific transcriptional signatures in human depression. Nat Med. 2017;23(9):1102-1111.
Understanding the epigenetic basis of sex differences in depression. J Neurosci Res. 2017;95(1-2):692-702.
Alterations of the Host Microbiome Affect Behavioral Responses to Cocaine. Sci Rep. 2016;6:35455.
Essential Role of Mesolimbic Brain-Derived Neurotrophic Factor in Chronic Social Stress-Induced Depressive Behaviors. Biol Psychiatry. 2016;80(6):469-78.
ACF chromatin-remodeling complex mediates stress-induced depressive-like behavior. Nat Med. 2015;21(10):1146-53.
Epigenetic basis of opiate suppression of Bdnf gene expression in the ventral tegmental area. Nat Neurosci. 2015;18(3):415-22.
Role of Tet1 and 5-hydroxymethylcytosine in cocaine action. Nat Neurosci. 2015;18(4):536-44.
Epigenetic signaling in psychiatric disorders. J Mol Biol. 2014;426(20):3389-412.
Epigenetic signaling in psychiatric disorders: stress and depression. Dialogues Clin Neurosci. 2014;16(3):281-95.
Fluoxetine epigenetically alters the CaMKIIα promoter in nucleus accumbens to regulate ΔFosB binding and antidepressant effects. Neuropsychopharmacology. 2014;39(5):1178-86.
Loss of BDNF signaling in D1R-expressing NAc neurons enhances morphine reward by reducing GABA inhibition. Neuropsychopharmacology. 2014;39(11):2646-53.