Export 113 results:
Filters: Author is J-P Julien [Clear All Filters]
Key role of UBQLN2 in pathogenesis of amyotrophic lateral sclerosis and frontotemporal dementia. Acta Neuropathol Commun. 2019;7(1):103.
Local Acceleration of Neurofilament Transport at Nodes of Ranvier. J Neurosci. 2019;39(4):663-677.
Virus-mediated delivery of antibody targeting TAR DNA-binding protein-43 mitigates associated neuropathology. J Clin Invest. 2019;129(4):1581-1595.
Chronic Administration of Pimozide Fails to Attenuate Motor and Pathological Deficits in Two Mouse Models of Amyotrophic Lateral Sclerosis. Neurotherapeutics. 2018;15(3):715-727.
Misfolded SOD1 pathology in sporadic Amyotrophic Lateral Sclerosis. Sci Rep. 2018;8(1):14223.
Neurofilament light interaction with GluN1 modulates neurotransmission and schizophrenia-associated behaviors. Transl Psychiatry. 2018;8(1):167.
Neuronal Expression of UBQLN2 Exacerbates TDP-43 Pathology in TDP-43 Mice through Interaction with Ubiquitin. Mol Neurobiol. 2018.
Overexpressed wild-type superoxide dismutase 1 exhibits amyotrophic lateral sclerosis-related misfolded conformation in induced pluripotent stem cell-derived spinal motor neurons. Neuroreport. 2018;29(1):25-29.
Protective effects of Withania somnifera extract in SOD1 mouse model of amyotrophic lateral sclerosis. Exp Neurol. 2018;309:193-204.
Neuroleptics as therapeutic compounds stabilizing neuromuscular transmission in amyotrophic lateral sclerosis. JCI Insight. 2017;2(22).
The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis. Sci Transl Med. 2017;9(391).
Exosome secretion is a key pathway for clearance of pathological TDP-43. Brain. 2016;139(Pt 12):3187-3201.
From animal models to human disease: a genetic approach for personalized medicine in ALS. Acta Neuropathol Commun. 2016;4(1):70.
Intermediate filament aggregates cause mitochondrial dysmotility and increase energy demands in giant axonal neuropathy. Hum Mol Genet. 2016.
MTHFSD and DDX58 are novel RNA-binding proteins abnormally regulated in amyotrophic lateral sclerosis. Brain. 2016;139(Pt 1):86-100.
Neurofilament depletion improves microtubule dynamics via modulation of Stat3/stathmin signaling. Acta Neuropathol. 2016;132(1):93-110.
Sex-dependent effects of chromogranin B P413L allelic variant as disease modifier in amyotrophic lateral sclerosis. Hum Mol Genet. 2016.
Sex-dependent effects of chromogranin B P413L allelic variant as disease modifier in amyotrophic lateral sclerosis. Hum Mol Genet. 2016;25(21):4771-4786.
CD11b+Ly6G- myeloid cells mediate mechanical inflammatory pain hypersensitivity. Proc Natl Acad Sci USA. 2015;112(49):E6808-17.
Dissociation of Axonal Neurofilament Content from Its Transport Rate. PLoS ONE. 2015;10(7):e0133848.
Early and persistent abnormal decoding by glial cells at the neuromuscular junction in an ALS model. J Neurosci. 2015;35(2):688-706.
Early-stage treatment with Withaferin A reduces levels of misfolded superoxide dismutase 1 and extends lifespan in a mouse model of amyotrophic lateral sclerosis. Neurotherapeutics. 2015;12(1):217-33.
Functions of neurofilaments in synapses. Mol Psychiatry. 2015;20(8):915.
Inflammation Induces TDP-43 Mislocalization and Aggregation. PLoS ONE. 2015;10(10):e0140248.