Publications
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“Novel G1481V and Q1491H SCN5A Mutations Linked to Long QT Syndrome Destabilize the Nav1.5 Inactivation State.”, CJC Open, vol. 3, no. 3, pp. 256-266, 2021.
, “A leaky voltage sensor domain of cardiac sodium channels causes arrhythmias associated with dilated cardiomyopathy.”, Sci Rep, vol. 8, no. 1, p. 13804, 2018.
, “A New Cardiac Channelopathy: From Clinical Phenotypes to Molecular Mechanisms Associated With Na1.5 Gating Pores.”, Front Cardiovasc Med, vol. 5, p. 139, 2018.
, “Biophysical, Molecular, and Pharmacological Characterization of Voltage-Dependent Sodium Channels From Induced Pluripotent Stem Cell-Derived Cardiomyocytes.”, Can J Cardiol, vol. 33, no. 2, pp. 269-278, 2017.
, “Induced pluripotent stem-cell-derived cardiomyocytes: cardiac applications, opportunities, and challenges.”, Can J Physiol Pharmacol, vol. 95, no. 10, pp. 1108-1116, 2017.
, “Biophysical characterization of the honeybee DSC1 orthologue reveals a novel voltage-dependent Ca2+ channel subfamily: CaV4.”, J Gen Physiol, vol. 148, no. 2, pp. 133-45, 2016.
, “Characterization of the honeybee AmNaV1 channel and tools to assess the toxicity of insecticides.”, Sci Rep, vol. 5, p. 12475, 2015.
, “Gating pore currents, a new pathological mechanism underlying cardiac arrhythmias associated with dilated cardiomyopathy.”, Channels (Austin), vol. 9, no. 3, pp. 139-44, 2015.
, “Gating pore currents are defects in common with two Nav1.5 mutations in patients with mixed arrhythmias and dilated cardiomyopathy.”, J Gen Physiol, vol. 145, no. 2, pp. 93-106, 2015.
, “Mutations in the Voltage Sensors of Domains I and II of Nav1.5 that are Associated with Arrhythmias and Dilated Cardiomyopathy Generate Gating Pore Currents.”, Front Pharmacol, vol. 6, p. 301, 2015.
, “[Omega pore, an alternative ion channel permeation pathway involved in the development of several channelopathies].”, Med Sci (Paris), vol. 31, no. 8-9, pp. 735-41, 2015.
, “Biophysics, pathophysiology, and pharmacology of ion channel gating pores.”, Front Pharmacol, vol. 5, p. 53, 2014.
, “Molecular biology and biophysical properties of ion channel gating pores.”, Q Rev Biophys, vol. 47, no. 4, pp. 364-88, 2014.
, “Nav 1.5 mutations linked to dilated cardiomyopathy phenotypes: Is the gating pore current the missing link?”, Channels (Austin), vol. 8, no. 1, pp. 90-4, 2014.
, “Novel SCN5A mutations in two families with "Brugada-like" ST elevation in the inferior leads and conduction disturbances.”, J Interv Card Electrophysiol, vol. 37, no. 2, pp. 131-40, 2013.
, “Sodium overload due to a persistent current that attenuates the arrhythmogenic potential of a novel LQT3 mutation.”, Front Pharmacol, vol. 4, p. 126, 2013.
, “Gating pore currents and the resting state of Nav1.4 voltage sensor domains.”, Proc Natl Acad Sci U S A, vol. 109, no. 47, pp. 19250-5, 2012.
, “Mexiletine differentially restores the trafficking defects caused by two brugada syndrome mutations.”, Front Pharmacol, vol. 3, p. 62, 2012.
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