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Publications

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2018
Pozzi S, Thammisetty SS, J-P Julien. Chronic Administration of Pimozide Fails to Attenuate Motor and Pathological Deficits in Two Mouse Models of Amyotrophic Lateral Sclerosis. Neurotherapeutics. 2018;15(3):715-727.
Paré B, Lehmann M, Beaudin M, Nordström U, Saikali S, J-P Julien, et al. Misfolded SOD1 pathology in sporadic Amyotrophic Lateral Sclerosis. Sci Rep. 2018;8(1):14223.
Yuan A, Sershen H, Basavarajappa BS, Smiley JF, Hashim A, Bleiwas C, et al. Neurofilament light interaction with GluN1 modulates neurotransmission and schizophrenia-associated behaviors. Transl Psychiatry. 2018;8(1):167.
Picher-Martel V, Renaud L, Bareil C, J-P Julien. Neuronal Expression of UBQLN2 Exacerbates TDP-43 Pathology in TDP-43 Mice through Interaction with Ubiquitin. Mol Neurobiol. 2018.
Komatsu K, Imamura K, Yamashita H, J-P Julien, Takahashi R, Inoue H. Overexpressed wild-type superoxide dismutase 1 exhibits amyotrophic lateral sclerosis-related misfolded conformation in induced pluripotent stem cell-derived spinal motor neurons. Neuroreport. 2018;29(1):25-29.
Dutta K, Patel P, J-P Julien. Protective effects of Withania somnifera extract in SOD1 mouse model of amyotrophic lateral sclerosis. Exp Neurol. 2018;309:193-204.
2016
Iguchi Y, Eid L, Parent M, Soucy G, Bareil C, Riku Y, et al. Exosome secretion is a key pathway for clearance of pathological TDP-43. Brain. 2016;139(Pt 12):3187-3201.
Picher-Martel V, Valdmanis PN, Gould PV, J-P Julien, Dupré N. From animal models to human disease: a genetic approach for personalized medicine in ALS. Acta Neuropathol Commun. 2016;4(1):70.
Israeli E, Dryanovski DI, Schumacker PT, Chandel NS, Singer JD, J-P Julien, et al. Intermediate filament aggregates cause mitochondrial dysmotility and increase energy demands in giant axonal neuropathy. Hum Mol Genet. 2016.
MacNair L, Xiao S, Miletic D, Ghani M, J-P Julien, Keith J, et al. MTHFSD and DDX58 are novel RNA-binding proteins abnormally regulated in amyotrophic lateral sclerosis. Brain. 2016;139(Pt 1):86-100.
Yadav P, Selvaraj BT, Bender FL, Behringer M, Moradi M, Sivadasan R, et al. Neurofilament depletion improves microtubule dynamics via modulation of Stat3/stathmin signaling. Acta Neuropathol. 2016;132(1):93-110.
Ohta Y, Soucy G, Phaneuf D, Audet J-, Gros-Louis F, Rouleau GA, et al. Sex-dependent effects of chromogranin B P413L allelic variant as disease modifier in amyotrophic lateral sclerosis. Hum Mol Genet. 2016.
Ohta Y, Soucy G, Phaneuf D, Audet J-, Gros-Louis F, Rouleau GA, et al. Sex-dependent effects of chromogranin B P413L allelic variant as disease modifier in amyotrophic lateral sclerosis. Hum Mol Genet. 2016;25(21):4771-4786.

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