Publications
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, “Induction of autophagy mitigates TDP-43 pathology and translational repression of neurofilament mRNAs in mouse models of ALS/FTD.”, Mol Neurodegener, vol. 16, no. 1, p. 1, 2021.
, “Targeting TDP-43 Pathology Alleviates Cognitive and Motor Deficits Caused by Chronic Cerebral Hypoperfusion.”, Neurotherapeutics, vol. 18, no. 2, pp. 1095-1112, 2021.
, “TDP-43 triggers immune response via mitochondrial DNA release.”, Cell Res, vol. 31, no. 4, pp. 379-380, 2021.
, “Withaferin-A Treatment Alleviates TAR DNA-Binding Protein-43 Pathology and Improves Cognitive Function in a Mouse Model of FTLD.”, Neurotherapeutics, vol. 18, no. 1, pp. 286-296, 2021.
, “Mitigation of ALS Pathology by Neuron-Specific Inhibition of Nuclear Factor Kappa B Signaling.”, J Neurosci, vol. 40, no. 26, pp. 5137-5154, 2020.
, “Monoclonal full-length antibody against TAR DNA-binding protein 43 reduces related proteinopathy in neurons.”, JCI Insight, 2020.
, “Neurofilaments: neurobiological foundations for biomarker applications.”, Brain, vol. 143, no. 7, pp. 1975-1998, 2020.
, “Transmission of ALS pathogenesis by the cerebrospinal fluid”, Acta neuropathologica communications, vol. 8, no. 1, pp. 65 - 65, 2020.
, “Transmission of ALS pathogenesis by the cerebrospinal fluid.”, Acta Neuropathol Commun, vol. 8, no. 1, p. 65, 2020.
, “Key role of UBQLN2 in pathogenesis of amyotrophic lateral sclerosis and frontotemporal dementia.”, Acta Neuropathol Commun, vol. 7, no. 1, p. 103, 2019.
, “Local Acceleration of Neurofilament Transport at Nodes of Ranvier.”, J Neurosci, vol. 39, no. 4, pp. 663-677, 2019.
, “Virus-mediated delivery of antibody targeting TAR DNA-binding protein-43 mitigates associated neuropathology.”, J Clin Invest, vol. 129, no. 4, pp. 1581-1595, 2019.
, “Chronic Administration of Pimozide Fails to Attenuate Motor and Pathological Deficits in Two Mouse Models of Amyotrophic Lateral Sclerosis.”, Neurotherapeutics, vol. 15, no. 3, pp. 715-727, 2018.
, “Misfolded SOD1 pathology in sporadic Amyotrophic Lateral Sclerosis.”, Sci Rep, vol. 8, no. 1, p. 14223, 2018.
, “Neurofilament light interaction with GluN1 modulates neurotransmission and schizophrenia-associated behaviors.”, Transl Psychiatry, vol. 8, no. 1, p. 167, 2018.
, “Neuronal Expression of UBQLN2 Exacerbates TDP-43 Pathology in TDP-43 Mice through Interaction with Ubiquitin.”, Mol Neurobiol, 2018.
, “Overexpressed wild-type superoxide dismutase 1 exhibits amyotrophic lateral sclerosis-related misfolded conformation in induced pluripotent stem cell-derived spinal motor neurons.”, Neuroreport, vol. 29, no. 1, pp. 25-29, 2018.
, “Protective effects of Withania somnifera extract in SOD1 mouse model of amyotrophic lateral sclerosis.”, Exp Neurol, vol. 309, pp. 193-204, 2018.
, “Neuroleptics as therapeutic compounds stabilizing neuromuscular transmission in amyotrophic lateral sclerosis.”, JCI Insight, vol. 2, no. 22, 2017.
, “The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis.”, Sci Transl Med, vol. 9, no. 391, 2017.
, “Withania somnifera Reverses Transactive Response DNA Binding Protein 43 Proteinopathy in a Mouse Model of Amyotrophic Lateral Sclerosis/Frontotemporal Lobar Degeneration.”, Neurotherapeutics, vol. 14, no. 2, pp. 447-462, 2017.
, “Exosome secretion is a key pathway for clearance of pathological TDP-43.”, Brain, vol. 139, no. Pt 12, pp. 3187-3201, 2016.
, “From animal models to human disease: a genetic approach for personalized medicine in ALS.”, Acta Neuropathol Commun, vol. 4, no. 1, p. 70, 2016.
, “Intermediate filament aggregates cause mitochondrial dysmotility and increase energy demands in giant axonal neuropathy.”, Hum Mol Genet, 2016.
, “MTHFSD and DDX58 are novel RNA-binding proteins abnormally regulated in amyotrophic lateral sclerosis.”, Brain, vol. 139, no. Pt 1, pp. 86-100, 2016.
