Publications

2022

“Comparative Transcriptional Analyses in the Nucleus Accumbens Identifies RGS2 as a Key Mediator of Depression-Related Behavior.”, Biol Psychiatry, vol. 92, no. 12, pp. 942-951, 2022.

“Sex-Specific Brain Transcriptional Signatures in Human MDD and Their Correlates in Mouse Models of Depression.”, Front Behav Neurosci, vol. 16, p. 845491, 2022.

2021

T. P. Bittar, Pelaez, M. Carmen, Silva, J. Cesar Hern, Quessy, F., Lavigne, A. - A., Morency, D., Blanchette, L. - J., Arsenault, E., Cherasse, Y., Seigneur, J., Timofeev, I., Sephton, C. F., Proulx, C. D., and Labonte, B., “Chronic Stress Induces Sex-Specific Functional and Morphological Alterations in Corticoaccumbal and Corticotegmental Pathways.”, Biol Psychiatry, vol. 90, no. 3, pp. 194-205, 2021.

T. P. Bittar and Labonte, B., “Functional Contribution of the Medial Prefrontal Circuitry in Major Depressive Disorder and Stress-Induced Depressive-Like Behaviors.”, Front Behav Neurosci, vol. 15, p. 699592, 2021.

“Methylation of the tyrosine hydroxylase gene is dysregulated by cocaine dependence in the human striatum.”, iScience, vol. 24, no. 10, p. 103169, 2021.

E. Arsenault, Lavigne, A. - A., Mansouri, S., Gagné, A. - M., Francis, K., Bittar, T. P., Quessy, F., Abdallah, K., Barbeau, A., Hébert, M., and Labonte, B., “Sex-Specific Retinal Anomalies Induced by Chronic Social Defeat Stress in Mice.”, Front Behav Neurosci, vol. 15, p. 714810, 2021.

2020

H. Yu, Villanueva, N., Bittar, T., Arsenault, E., Labonte, B., and Huan, T., “Parallel metabolomics and lipidomics enables the comprehensive study of mouse brain regional metabolite and lipid patterns.”, Anal Chim Acta, vol. 1136, pp. 168-177, 2020.

B. Labonte, Abdallah, K., Maussion, G., Yerko, V., Yang, J., Bittar, T., Quessy, F., Golden, S. A., Navarro, L., Checknita, D., Gigek, C., Lopez, J. Pablo, Neve, R. L., Russo, S. J., Tremblay, R. E., Côté, G., Meaney, M. J., Mechawar, N., Nestler, E. J., and Turecki, G., “Regulation of impulsive and aggressive behaviours by a novel lncRNA.”, Mol Psychiatry, 2020.

J. R. Scarpa, Fatma, M., Loh, Y. - H. E., Traore, S. Romaric, Stefan, T., Chen, T. - H., Nestler, E. J., and Labonte, B., “Shared Transcriptional Signatures in Major Depressive Disorder and Mouse Chronic Stress Models.”, Biol Psychiatry, vol. 88, no. 2, pp. 159-168, 2020.

2019

H. Kronman, Richter, F., Labonte, B., Chandra, R., Zhao, S., Hoffman, G., Lobo, M. Kay, Schadt, E. E., and Nestler, E. J., “Biology and Bias in Cell Type-Specific RNAseq of Nucleus Accumbens Medium Spiny Neurons.”, Sci Rep, vol. 9, no. 1, p. 8350, 2019.

B. Labonte, Jeong, Y. Ha, Parise, E., Issler, O., Fatma, M., Engmann, O., Cho, K. - A., Neve, R., Nestler, E. J., and Koo, J. Wook, “Gadd45b mediates depressive-like role through DNA demethylation.”, Sci Rep, vol. 9, no. 1, p. 4615, 2019.

Z. S. Lorsch, Hamilton, P. J., Ramakrishnan, A., Parise, E. M., Salery, M., Wright, W. J., Lepack, A. E., Mews, P., Issler, O., McKenzie, A., Zhou, X., Parise, L. F., Pirpinias, S. T., Torres, I. Ortiz, Kronman, H. G., Montgomery, S. E., Loh, Y. - H. Eddie, Labonte, B., Conkey, A., Symonds, A. E., Neve, R. L., Turecki, G., Maze, I., Dong, Y., Zhang, B., Shen, L., Bagot, R. C., and Nestler, E. J., “Stress resilience is promoted by a Zfp189-driven transcriptional network in prefrontal cortex.”, Nat Neurosci, vol. 22, no. 9, pp. 1413-1423, 2019.

C. Jiang, Lin, W. - J., Labonte, B., Tamminga, C. A., Turecki, G., Nestler, E. J., Russo, S. J., and Salton, S. R., “VGF and its C-terminal peptide TLQP-62 in ventromedial prefrontal cortex regulate depression-related behaviors and the response to ketamine.”, Neuropsychopharmacology, vol. 44, no. 5, pp. 971-981, 2019.

2018

B. Labonte, Engmann, O., Purushothaman, I., Menard, C., Wang, J., Tan, C., Scarpa, J. R., Moy, G., Loh, Y. - H. E., Cahill, M., Lorsch, Z. S., Hamilton, P. J., Calipari, E. S., Hodes, G. E., Issler, O., Kronman, H., Pfau, M., Obradovic, A. L. J., Dong, Y., Neve, R. L., Russo, S., Kasarskis, A., Tamminga, C., Mechawar, N., Turecki, G., Zhang, B., Shen, L., and Nestler, E. J., “Corrigendum: Sex-specific transcriptional signatures in human depression.”, Nat Med, vol. 24, no. 4, p. 525, 2018.

Z. S. Lorsch, Loh, Y. - H. Eddie, Purushothaman, I., Walker, D. M., Parise, E. M., Salery, M., Cahill, M. E., Hodes, G. E., Pfau, M. L., Kronman, H., Hamilton, P. J., Issler, O., Labonte, B., Symonds, A. E., Zucker, M., Zhang, T. Yuan, Meaney, M. J., Russo, S. J., Shen, L., Bagot, R. C., and Nestler, E. J., “Estrogen receptor α drives pro-resilient transcription in mouse models of depression.”, Nat Commun, vol. 9, no. 1, p. 1116, 2018.

B. Labonte, “The Opioid System as a Long-Lasting Molecular Witness of Child Abuse in the Brain.”, Biol Psychiatry, vol. 84, no. 10, pp. 706-707, 2018.

2017

O. Engmann, Labonte, B., Mitchell, A., Bashtrykov, P., Calipari, E. S., Rosenbluh, C., Loh, Y. - H. E., Walker, D. M., Burek, D., Hamilton, P. J., Issler, O., Neve, R. L., Turecki, G., Hurd, Y., Chess, A., Shen, L., Mansuy, I., Jeltsch, A., Akbarian, S., and Nestler, E. J., “Cocaine-Induced Chromatin Modifications Associate With Increased Expression and Three-Dimensional Looping of Auts2.”, Biol Psychiatry, 2017.

R. C. Bagot, Cates, H. M., Purushothaman, I., Vialou, V., Heller, E. A., Yieh, L., Labonte, B., Peña, C. J., Shen, L., Wittenberg, G. M., and Nestler, E. J., “Ketamine and Imipramine Reverse Transcriptional Signatures of Susceptibility and Induce Resilience-Specific Gene Expression Profiles.”, Biol Psychiatry, vol. 81, no. 4, pp. 285-295, 2017.

Y. Jiang, Loh, Y. - H. Eddie, Rajarajan, P., Hirayama, T., Liao, W., Kassim, B. S., Javidfar, B., Hartley, B. J., Kleofas, L., Park, R. B., Labonte, B., Ho, S. - M., Chandrasekaran, S., Do, C., Ramirez, B. R., Peter, C. J., W, J. T. C., Safaie, B. M., Morishita, H., Roussos, P., Nestler, E. J., Schaefer, A., Tycko, B., Brennand, K. J., Yagi, T., Shen, L., and Akbarian, S., “The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain.”, Nat Genet, vol. 49, no. 8, pp. 1239-1250, 2017.

J. Pablo Lopez, Fiori, L. M., Cruceanu, C., Lin, R., Labonte, B., Cates, H. M., Heller, E. A., Vialou, V., Ku, S. M., Gerald, C., Han, M. - H., Foster, J., Frey, B. N., Soares, C. N., Müller, D. J., Farzan, F., Leri, F., MacQueen, G. M., Feilotter, H., Tyryshkin, K., Evans, K. R., Giacobbe, P., Blier, P., Lam, R. W., Milev, R., Parikh, S. V., Rotzinger, S., Strother, S. C., Lewis, C. M., Aitchison, K. J., Wittenberg, G. M., Mechawar, N., Nestler, E. J., Uher, R., Kennedy, S. H., and Turecki, G., “MicroRNAs 146a/b-5 and 425-3p and 24-3p are markers of antidepressant response and regulate MAPK/Wnt-system genes.”, Nat Commun, vol. 8, p. 15497, 2017.

B. Labonte, Engmann, O., Purushothaman, I., Menard, C., Wang, J., Tan, C., Scarpa, J. R., Moy, G., Loh, Y. - H. E., Cahill, M., Lorsch, Z. S., Hamilton, P. J., Calipari, E. S., Hodes, G. E., Issler, O., Kronman, H., Pfau, M., Obradovic, A. L. J., Dong, Y., Neve, R. L., Russo, S., Kazarskis, A., Tamminga, C., Mechawar, N., Turecki, G., Zhang, B., Shen, L., and Nestler, E. J., “Sex-specific transcriptional signatures in human depression.”, Nat Med, vol. 23, no. 9, pp. 1102-1111, 2017.

C. Menard, Pfau, M. L., Hodes, G. E., Kana, V., Wang, V. X., Bouchard, S., Takahashi, A., Flanigan, M. E., Aleyasin, H., LeClair, K. B., Janssen, W. G., Labonte, B., Parise, E. M., Lorsch, Z. S., Golden, S. A., Heshmati, M., Tamminga, C., Turecki, G., Campbell, M., Fayad, Z. A., Tang, C. Ying, Merad, M., and Russo, S. J., “Social stress induces neurovascular pathology promoting depression.”, Nat Neurosci, vol. 20, no. 12, pp. 1752-1760, 2017.

G. E. Hodes, Walker, D. M., Labonte, B., Nestler, E. J., and Russo, S. J., “Understanding the epigenetic basis of sex differences in depression.”, J Neurosci Res, vol. 95, no. 1-2, pp. 692-702, 2017.

C. Jiang, Lin, W. - J., Sadahiro, M., Labonte, B., Menard, C., Pfau, M. L., Tamminga, C. A., Turecki, G., Nestler, E. J., Russo, S. J., and Salton, S. R., “VGF function in depression and antidepressant efficacy.”, Mol Psychiatry, 2017.

2016

D. D. Kiraly, Walker, D. M., Calipari, E. S., Labonte, B., Issler, O., Peña, C. J., Ribeiro, E. A., Russo, S. J., and Nestler, E. J., “Alterations of the Host Microbiome Affect Behavioral Responses to Cocaine.”, Sci Rep, vol. 6, p. 35455, 2016.

Publications

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