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2014
M. E. Ward, Taubes, A., Chen, R., Miller, B. L., Sephton, C. F., Gelfand, J. M., Minami, S., Boscardin, J., Martens, L. Herl, Seeley, W. W., Yu, G., Herz, J., Filiano, A. J., Arrant, A. E., Roberson, E. D., Kraft, T. W., Farese, R. V., Green, A., and Gan, L., Early retinal neurodegeneration and impaired Ran-mediated nuclear import of TDP-43 in progranulin-deficient FTLD., J Exp Med, vol. 211, no. 10, pp. 1937-45, 2014.
H. Poulin, Bruhova, I., Timour, Q., Thériault, O., Beaulieu, J. - M., Frassati, D., and Chahine, M., Fluoxetine blocks Nav1.5 channels via a mechanism similar to that of class 1 antiarrhythmics., Mol Pharmacol, vol. 86, no. 4, pp. 378-89, 2014.
P. Jourdain, Becq, F., Lengacher, S., Boinot, C., Magistretti, P. J., and Marquet, P., The human CFTR protein expressed in CHO cells activates aquaporin-3 in a cAMP-dependent pathway: study by digital holographic microscopy., J Cell Sci, vol. 127, no. Pt 3, pp. 546-56, 2014.
P. Gosselin-Badaroudine, Moreau, A., and Chahine, M., Nav 1.5 mutations linked to dilated cardiomyopathy phenotypes: Is the gating pore current the missing link?, Channels (Austin), vol. 8, no. 1, pp. 90-4, 2014.
A. Mechakra, Vincent, Y., Chevalier, P., Millat, G., Ficker, E., Jastrzebski, M., Poulin, H., Pouliot, V., Chahine, M., and Christé, G., The variant hERG/R148W associated with LQTS is a mutation that reduces current density on co-expression with the WT., Gene, vol. 536, no. 2, pp. 348-56, 2014.
A. Bureau, Parker, M. M., Ruczinski, I., Taub, M. A., Marazita, M. L., Murray, J. C., Mangold, E., Noethen, M. M., Ludwig, K. U., Hetmanski, J. B., Bailey-Wilson, J. E., Cropp, C. D., Li, Q., Szymczak, S., Albacha-Hejazi, H., Alqosayer, K., L Field, L., Wu-Chou, Y. - H., Doheny, K. F., Ling, H., Scott, A. F., and Beaty, T. H., Whole exome sequencing of distant relatives in multiplex families implicates rare variants in candidate genes for oral clefts., Genetics, vol. 197, no. 3, pp. 1039-44, 2014.
2012
P. Gosselin-Badaroudine, Delemotte, L., Moreau, A., Klein, M. L., and Chahine, M., Gating pore currents and the resting state of Nav1.4 voltage sensor domains., Proc Natl Acad Sci U S A, vol. 109, no. 47, pp. 19250-5, 2012.
T. E. Brotherton, Li, Y., Cooper, D., Gearing, M., J-P Julien, Rothstein, J. D., Boylan, K., and Glass, J. D., Localization of a toxic form of superoxide dismutase 1 protein to pathologically affected tissues in familial ALS., Proc Natl Acad Sci U S A, vol. 109, no. 14, pp. 5505-10, 2012.
B. J. Gentil, Minotti, S., Beange, M., Baloh, R. H., J-P Julien, and Durham, H. D., Normal role of the low-molecular-weight neurofilament protein in mitochondrial dynamics and disruption in Charcot-Marie-Tooth disease., FASEB J, vol. 26, no. 3, pp. 1194-203, 2012.
B. Cenik, Sephton, C. F., Cenik, B. Kutluk, Herz, J., and Yu, G., Progranulin: a proteolytically processed protein at the crossroads of inflammation and neurodegeneration., J Biol Chem, vol. 287, no. 39, pp. 32298-306, 2012.
P. Gosselin-Badaroudine, Keller, D. I., Huang, H., Pouliot, V., Chatelier, A., Osswald, S., Brink, M., and Chahine, M., A proton leak current through the cardiac sodium channel is linked to mixed arrhythmia and the dilated cardiomyopathy phenotype., PLoS One, vol. 7, no. 5, p. e38331, 2012.
J. Raingo, Khvotchev, M., Liu, P., Darios, F., Li, Y. C., Ramirez, D. M. O., Adachi, M., Lemieux, P., Tóth, K., Davletov, B., and Kavalali, E. T., VAMP4 directs synaptic vesicles to a pool that selectively maintains asynchronous neurotransmission., Nat Neurosci, vol. 15, no. 5, pp. 738-45, 2012.

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