Publications

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2007
J-P Julien, ALS: astrocytes move in as deadly neighbors., Nat Neurosci, vol. 10, no. 5, pp. 535-7, 2007.
J-P Julien and Kriz, J., Chapter 6 Animal models of motor neuron death., Handb Clin Neurol, vol. 82, pp. 121-38, 2007.
S. Millecamps, Gowing, G., Corti, O., Mallet, J., and J-P Julien, Conditional NF-L transgene expression in mice for in vivo analysis of turnover and transport rate of neurofilaments., J Neurosci, vol. 27, no. 18, pp. 4947-56, 2007.
J. Zhai, Lin, H., J-P Julien, and Schlaepfer, W. W., Disruption of neurofilament network with aggregation of light neurofilament protein: a common pathway leading to motor neuron degeneration due to Charcot-Marie-Tooth disease-linked mutations in NFL and HSPB1., Hum Mol Genet, vol. 16, no. 24, pp. 3103-16, 2007.
H. Galarneau, Villeneuve, J., Gowing, G., J-P Julien, and Vallières, L., Increased glioma growth in mice depleted of macrophages., Cancer Res, vol. 67, no. 18, pp. 8874-81, 2007.
M. Barclay, Noakes, P. G., Ryan, A. F., J-P Julien, and Housley, G. D., Neuronal expression of peripherin, a type III intermediate filament protein, in the mouse hindbrain., Histochem Cell Biol, vol. 128, no. 6, pp. 541-50, 2007.
D. M. Barry, Millecamps, S., J-P Julien, and Garcia, M. L., New movements in neurofilament transport, turnover and disease., Exp Cell Res, vol. 313, no. 10, pp. 2110-20, 2007.
M. Urushitani, Ezzi, S. Abou, and J-P Julien, Therapeutic effects of immunization with mutant superoxide dismutase in mice models of amyotrophic lateral sclerosis., Proc Natl Acad Sci U S A, vol. 104, no. 7, pp. 2495-500, 2007.
C. Haenggeli, J-P Julien, R Mosley, L., Perez, N., Dhar, A., Gendelman, H. E., and Rothstein, J. D., Therapeutic immunization with a glatiramer acetate derivative does not alter survival in G93A and G37R SOD1 mouse models of familial ALS., Neurobiol Dis, vol. 26, no. 1, pp. 146-52, 2007.
S. Abou Ezzi, Urushitani, M., and J-P Julien, Wild-type superoxide dismutase acquires binding and toxic properties of ALS-linked mutant forms through oxidation., J Neurochem, vol. 102, no. 1, pp. 170-8, 2007.
2006
G. Gowing, Dequen, F., Soucy, G., and J-P Julien, Absence of tumor necrosis factor-alpha does not affect motor neuron disease caused by superoxide dismutase 1 mutations., J Neurosci, vol. 26, no. 44, pp. 11397-402, 2006.
T. Sasaki, Gotow, T., Shiozaki, M., Sakaue, F., Saito, T., J-P Julien, Uchiyama, Y., and Hisanaga, S. - I., Aggregate formation and phosphorylation of neurofilament-L Pro22 Charcot-Marie-Tooth disease mutants., Hum Mol Genet, vol. 15, no. 6, pp. 943-52, 2006.
A. Yuan, Rao, M. V., Sasaki, T., Chen, Y., Kumar, A., Liem, R. K. H., Eyer, J., Peterson, A. C., J-P Julien, and Nixon, R. A., Alpha-internexin is structurally and functionally associated with the neurofilament triplet proteins in the mature CNS., J Neurosci, vol. 26, no. 39, pp. 10006-19, 2006.
J. Carmen, Gowing, G., J-P Julien, and Kerr, D., Altered immune response to CNS viral infection in mice with a conditional knock-down of macrophage-lineage cells., Glia, vol. 54, no. 2, pp. 71-80, 2006.
A. R. Simard, Soulet, D., Gowing, G., J-P Julien, and Rivest, S., Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease., Neuron, vol. 49, no. 4, pp. 489-502, 2006.
M. Urushitani, Sík, A., Sakurai, T., Nukina, N., Takahashi, R., and J-P Julien, Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis., Nat Neurosci, vol. 9, no. 1, pp. 108-18, 2006.
S. Millecamps, Robertson, J., Larivière, R., Mallet, J., and J-P Julien, Defective axonal transport of neurofilament proteins in neurons overexpressing peripherin., J Neurochem, vol. 98, no. 3, pp. 926-38, 2006.
G. Gowing, Vallières, L., and J-P Julien, Mouse model for ablation of proliferating microglia in acute CNS injuries., Glia, vol. 53, no. 3, pp. 331-7, 2006.
J-P Julien and Kriz, J., Transgenic mouse models of amyotrophic lateral sclerosis., Biochim Biophys Acta, vol. 1762, no. 11-12, pp. 1013-24, 2006.

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