Publications
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“NPRL2 Inhibition of mTORC1 Controls Sodium Channel Expression and Brain Amino Acid Homeostasis.”, eNeuro, vol. 9, no. 2, 2022.
“A postzygotic de novo NCDN mutation identified in a sporadic FTLD patient results in neurochondrin haploinsufficiency and altered FUS granule dynamics.”, Acta Neuropathol Commun, vol. 10, no. 1, p. 20, 2022.
“Synaptic dysfunction in ALS and FTD: anatomical and molecular changes provide insights into mechanisms of disease.”, Front Mol Neurosci, vol. 15, p. 1000183, 2022.
, “Widespread alterations in microRNA biogenesis in human Huntington's disease putamen.”, Acta Neuropathol Commun, vol. 10, no. 1, p. 106, 2022.
, “Chronic Stress Induces Sex-Specific Functional and Morphological Alterations in Corticoaccumbal and Corticotegmental Pathways.”, Biol Psychiatry, vol. 90, no. 3, pp. 194-205, 2021.
“hnRNP A1B, a Splice Variant of , Is Spatially and Temporally Regulated.”, Front Neurosci, vol. 15, p. 724307, 2021.
, “FUS contributes to mTOR-dependent inhibition of translation.”, J Biol Chem, vol. 295, no. 52, pp. 18459-18473, 2020.
, “Metabolic Networks Influencing Skeletal Muscle Fiber Composition.”, Front Cell Dev Biol, vol. 6, p. 125, 2018.
, “The function of RNA-binding proteins at the synapse: implications for neurodegeneration.”, Cell Mol Life Sci, vol. 72, no. 19, pp. 3621-35, 2015.
, “Activity-dependent FUS dysregulation disrupts synaptic homeostasis.”, Proc Natl Acad Sci U S A, vol. 111, no. 44, pp. E4769-78, 2014.
, “Early retinal neurodegeneration and impaired Ran-mediated nuclear import of TDP-43 in progranulin-deficient FTLD.”, J Exp Med, vol. 211, no. 10, pp. 1937-45, 2014.
, “Progranulin: a proteolytically processed protein at the crossroads of inflammation and neurodegeneration.”, J Biol Chem, vol. 287, no. 39, pp. 32298-306, 2012.
, “TDP-43 aggregation in neurodegeneration: are stress granules the key?”, Brain Res, vol. 1462, pp. 16-25, 2012.
, “TDP-43 in central nervous system development and function: clues to TDP-43-associated neurodegeneration.”, Biol Chem, vol. 393, no. 7, pp. 589-94, 2012.
, “Gamma-secretase-regulated proteolysis of the Notch receptor by mitochondrial intermediate peptidase.”, J Biol Chem, vol. 286, no. 31, pp. 27447-53, 2011.
, “Identification of neuronal RNA targets of TDP-43-containing ribonucleoprotein complexes.”, J Biol Chem, vol. 286, no. 2, pp. 1204-15, 2011.
, “Suberoylanilide hydroxamic acid (vorinostat) up-regulates progranulin transcription: rational therapeutic approach to frontotemporal dementia.”, J Biol Chem, vol. 286, no. 18, pp. 16101-8, 2011.
, “TDP-43 is directed to stress granules by sorbitol, a novel physiological osmotic and oxidative stressor.”, Mol Cell Biol, vol. 31, no. 5, pp. 1098-108, 2011.
, “TDP-43 is a developmentally regulated protein essential for early embryonic development.”, J Biol Chem, vol. 285, no. 9, pp. 6826-34, 2010.
, “Abeta predictor of Alzheimer disease symptoms.”, Arch Neurol, vol. 65, no. 7, pp. 875-6, 2008.
, “Haloperidol induces the nuclear translocation of phosphatidylinositol 3'-kinase to disrupt Akt phosphorylation in PC12 cells.”, J Psychiatry Neurosci, vol. 32, no. 5, pp. 323-30, 2007.
