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2022

“Microglia-mediated degradation of perineuronal nets promotes pain.”, Science, vol. 377, no. 6601, pp. 80-86, 2022.

2020

F. Ferrini, Perez-Sanchez, J., Ferland, S., Lorenzo, L. - E., Godin, A. G., Plasencia-Fernandez, I., Cottet, M., Castonguay, A., Wang, F., Salio, C., Doyon, N., Merighi, A., and De Koninck, Y., “Differential chloride homeostasis in the spinal dorsal horn locally shapes synaptic metaplasticity and modality-specific sensitization.”, Nat Commun, vol. 11, no. 1, p. 3935, 2020.

W. Dong, Jin, S. Chih, Allocco, A., Zeng, X., Sheth, A. H., Panchagnula, S., Castonguay, A., Lorenzo, L. - E., Islam, B., Brindle, G., Bachand, K., Hu, J., Sularz, A., Gaillard, J., Choi, J., Dunbar, A., Nelson-Williams, C., Kiziltug, E., Furey, C. Gavankar, Conine, S., Duy, P. Q., Kundishora, A. J., Loring, E., Li, B., Lu, Q., Zhou, G., Liu, W., Li, X., Sierant, M. C., Mane, S., Castaldi, C., López-Giráldez, F., Knight, J. R., Sekula, R. F., J Simard, M., Eskandar, E. N., Gottschalk, C., Moliterno, J., Günel, M., Gerrard, J. L., Dib-Hajj, S., Waxman, S. G., Barker, F. G., Alper, S. L., Chahine, M., Haider, S., De Koninck, Y., Lifton, R. P., and Kahle, K. T., “Exome Sequencing Implicates Impaired GABA Signaling and Neuronal Ion Transport in Trigeminal Neuralgia.”, iScience, vol. 23, no. 10, p. 101552, 2020.

2019

M. Richner, Pallesen, L. T., Ulrichsen, M., Poulsen, E. T., Holm, T. H., Login, H., Castonguay, A., Lorenzo, L. - E., Gonçalves, N. P., Andersen, O. M., Lykke-Hartmann, K., Enghild, J. J., Rønn, L. C. B., Malik, I. J., De Koninck, Y., Bjerrum, O. J., Vægter, C. B., and Nykjær, A., “Sortilin gates neurotensin and BDNF signaling to control peripheral neuropathic pain.”, Sci Adv, vol. 5, no. 6, p. eaav9946, 2019.

2017

M. Gagnon, Bergeron, M. J., Perez-Sanchez, J., Plasencia-Fernandez, I., Lorenzo, L. - E., Godin, A. G., Castonguay, A., Bonin, R. P., and De Koninck, Y., “Reply to The small molecule CLP257 does not modify activity of the K-Cl co-transporter KCC2 but does potentiate GABA receptor activity.”, Nat Med, vol. 23, no. 12, pp. 1396-1398, 2017.

2016

L. S. Miraucourt, Tsui, J., Gobert, D., Desjardins, J. - F., Schohl, A., Sild, M., Spratt, P., Castonguay, A., De Koninck, Y., Marsh-Armstrong, N., Wiseman, P. W., and Ruthazer, E. S., “Endocannabinoid signaling enhances visual responses through modulation of intracellular chloride levels in retinal ganglion cells.”, Elife, vol. 5, 2016.

A. M. W. Taylor, Castonguay, A., Ghogha, A., Vayssiere, P., Pradhan, A. A. A., Xue, L., Mehrabani, S., Wu, J., Levitt, P., Olmstead, M. C., De Koninck, Y., Evans, C. J., and Cahill, C. M., “Neuroimmune Regulation of GABAergic Neurons Within the Ventral Tegmental Area During Withdrawal from Chronic Morphine.”, Neuropsychopharmacology, vol. 41, no. 4, pp. 949-59, 2016.

2015

A. Ford, Castonguay, A., Cottet, M., Little, J. W., Chen, Z., Symons-Liguori, A. M., Doyle, T., Egan, T. M., Vanderah, T. W., De Koninck, Y., Tosh, D. K., Jacobson, K. A., and Salvemini, D., “Engagement of the GABA to KCC2 signaling pathway contributes to the analgesic effects of A3AR agonists in neuropathic pain.”, J Neurosci, vol. 35, no. 15, pp. 6057-67, 2015.

A. M. W. Taylor, Castonguay, A., Taylor, A. J., Murphy, N. P., Ghogha, A., Cook, C., Xue, L., Olmstead, M. C., De Koninck, Y., Evans, C. J., and Cahill, C. M., “Microglia disrupt mesolimbic reward circuitry in chronic pain.”, J Neurosci, vol. 35, no. 22, pp. 8442-50, 2015.

2014

G. Thériault, Cottet, M., Castonguay, A., McCarthy, N., and De Koninck, Y., “Extended two-photon microscopy in live samples with Bessel beams: steadier focus, faster volume scans, and simpler stereoscopic imaging.”, Front Cell Neurosci, vol. 8, p. 139, 2014.

M. J. Bergeron, Castonguay, A., and De Koninck, Y., “[KCC2: a new therapeutical target for the treatment of neurological diseases].”, Med Sci (Paris), vol. 30, no. 5, pp. 514-7, 2014.

2013

M. Gagnon, Bergeron, M. J., Lavertu, G., Castonguay, A., Tripathy, S., Bonin, R. P., Perez-Sanchez, J., Boudreau, D., Wang, B., Dumas, L., Valade, I., Bachand, K., Jacob-Wagner, M., Tardif, C., Kianicka, I., Isenring, P., Attardo, G., Coull, J. A. M., and De Koninck, Y., “Chloride extrusion enhancers as novel therapeutics for neurological diseases.”, Nat Med, vol. 19, no. 11, pp. 1524-8, 2013.

F. Ferrini, Trang, T., Mattioli, T. - A. M., Laffray, S., Del'Guidice, T., Lorenzo, L. - E., Castonguay, A., Doyon, N., Zhang, W., Godin, A. G., Mohr, D., Beggs, S., Vandal, K., Beaulieu, J. - M., Cahill, C. M., Salter, M. W., and De Koninck, Y., “Morphine hyperalgesia gated through microglia-mediated disruption of neuronal Cl⁻ homeostasis.”, Nat Neurosci, vol. 16, no. 2, pp. 183-92, 2013.

2012

B. Caillier, Pilote, S., Castonguay, A., Patoine, D., Ménard-Desrosiers, V., Vigneault, P., Hreiche, R., Turgeon, J., Daleau, P., De Koninck, Y., Simard, C., and Drolet, B., “QRS widening and QT prolongation under bupropion: a unique cardiac electrophysiological profile.”, Fundam Clin Pharmacol, vol. 26, no. 5, pp. 599-608, 2012.

2011

N. Doyon, Prescott, S. A., Castonguay, A., Godin, A. G., Kröger, H., and De Koninck, Y., “Efficacy of synaptic inhibition depends on multiple, dynamically interacting mechanisms implicated in chloride homeostasis.”, PLoS Comput Biol, vol. 7, no. 9, p. e1002149, 2011.

2006

P. Dufour, Dufour, S., Castonguay, A., McCarthy, N., and De Koninck, Y., “[Two-photon laser scanning fluorescence microscopy for functional cellular imaging: Advantages and challenges or One photon is good.. but two is better!].”, Med Sci (Paris), vol. 22, no. 10, pp. 837-44, 2006.

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