Sensitivity to voice in human prefrontal cortex.

Publication Type:

Journal Article


J Neurophysiol, Volume 94, Issue 3, p.2251-4 (2005)


Acoustic Stimulation, Adult, Auditory Perception, Auditory Threshold, Brain Mapping, Dose-Response Relationship, Radiation, Female, Humans, Image Processing, Computer-Assisted, Magnetic Resonance Imaging, Male, Oxygen, Prefrontal Cortex, Voice


<p>We report two functional MRI (fMRI) experiments showing sensitivity to human voice in a region of human left inferior prefrontal cortex, pars orbitalis. The voice-enhanced response was observed for speech as well as non-linguistic vocalizations and was stronger for emotional than neutral vocalizations. This region could constitute a human prefrontal auditory domain similar to the one recently identified in the macaque brain.</p>

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