Study of the structure and function of sodium channels in the brain and heart to identify new therapeutic targets to improve communication between cells.
Mohamed Chahine is a world-renowned expert on the structure, function and biophysical properties of sodium channels, which are channels on the surface of cells that allow entry and exit of sodium ions. Sodium channels are specifically found in the brain and the heart, where they affect the function of cells. Dr. Chahine's research has led to the characterization of sodium channels involved in several disorders including...
Using new imaging technologies to better understand evolution of neurodegenerative diseases such as multiple sclerosis
A physicist by training, Professor Daniel Côté works with neurobiologists to develop imaging technologies that can visualize brain cells and determine their level of activity, or that can help with surgery. This approach, based on the use of lasers, optical fibers and the application of complex physical principles, provides a better understanding of the functioning of the brain in health or disease.
The technologies developed by Dr. Côté's team have...
Synaptic transmission: from chronic pain to Alzheimer's disease
Yves De Koninck's work focuses on the transmission of signals from one neuron to another, also called synaptic transmission, and the necessary balance between excitatory and inhibitory signals in the brain and spinal cord. His research has shown how a normally benign stimulus can turn into a pain signal, leading to the development of chronic pain.
One person in five will experience chronic pain in their lifetime, a proportion that increases with age. This is the leading cause of disability in the country...
Reaching a deeper understanding of neurons and neural networks through mathematical simulation and modeling.
Professor Nicolas Doyon, from the Department of Mathematics and Statistics, uses his expertise in mathematical modeling to better understand how ion transporters influence signal processing by neurons. Precise control of the amounts of certain ions, such as chloride ions, is necessary for the proper functioning of neurons. Professor Doyon's studies have led to a better understanding of the spatio-temporal control of ion transport in neurons.
Defects in the...
The Social and Cognitive Neuroscience Laboratory was created by Professor Philip L. Jackson, full Professor at the School of Psychology at Laval University. The laboratory studies are carried out at the Interdisciplinary Center for Rehabilitation and Social Integration (CIRRIS), at the CERVO Research Center, and at the School of Psychology.
Members of the lab are interested in the human brain's ability to mentally represent others’ actions, emotions or states of mind. From a cognitive and social neuroscience perspective, his research program examines factors that may influence this...