Ting-Huei Chen

Recent Publications

Chen T-H, Chatterjee N, Landi MTeresa, Shi J. A penalized regression framework for building polygenic risk models based on summary statistics from genome-wide association studies and incorporating external information. J Am Stat Assoc. 2021;116(533):133-143.
Nugent S, Potvin O, Cunnane SC, Chen T-H, Duchesne S. Associating Type 2 Diabetes Risk Factor Genes and FDG-PET Brain Metabolism in Normal Aging and Alzheimer's Disease. Front Aging Neurosci. 2020;12:580633.
Chen T-H, Boughal H. A penalized structural equation modeling method accounting for secondary phenotypes for variable selection on genetically regulated expression from PrediXcan for Alzheimer's disease. Biometrics. 2020;.
Scarpa JR, Fatma M, Loh Y-HE, Traore SRomaric, Stefan T, Chen T-H, et al.. Shared Transcriptional Signatures in Major Depressive Disorder and Mouse Chronic Stress Models. Biol Psychiatry. 2020;88(2):159-168.
Mavaddat N, Michailidou K, Dennis J, Lush M, Fachal L, Lee A, et al.. Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes. Am J Hum Genet. 2019;104(1):21-34.
Gu F, Chen T-H, Pfeiffer RM, Fargnoli MConcetta, Calista D, Ghiorzo P, et al.. Combining common genetic variants and non-genetic risk factors to predict risk of cutaneous melanoma. Hum Mol Genet. 2018;27(23):4145-4156.
Morton LM, Sampson JN, Armstrong GT, Chen T-H, Hudson MM, Karlins E, et al.. Genome-Wide Association Study to Identify Susceptibility Loci That Modify Radiation-Related Risk for Breast Cancer After Childhood Cancer. J Natl Cancer Inst. 2017;109(11).
Chen T-H, Sun W. Prediction of cancer drug sensitivity using high-dimensional omic features. Biostatistics. 2017;18(1):1-14.
Chen T-H, Sun W, Fine JP. Designing penalty functions in high dimensional problems: The role of tuning parameters. Electron J Stat. 2016;10(2):2312-2328.
Sun W, Kechris K, Jacobson S, M Drummond B, Hawkins GA, Yang J, et al.. Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD. PLoS Genet. 2016;12(8):e1006011.

Funding / Support / Partners

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