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Cerebrovascular underpinnings of a neurodevelopmental disorder

Date et heure: 
Ven, 2018-09-28 11:00
Une conférence de: 
Baptiste Lacoste
Affiliation: 

Assistant Professor
Faculty of Medicine, Department of Cellular & Molecular Medicine
The Ottawa Hospital Research Institute, Neuroscience program
The University of Ottawa Brain and Mind Research Institute

Description: 

My research focuses on solving fundamental problems with state-of-the-art approaches and a strong translational perspective, and includes a combination of anatomical, physiological, biochemical and genetic approaches. 

Research themes

  • Development, structure and plasticity of neurovascular networks: physiological and pathological remodeling of the neurovascular unit. 
  • Cerebrovascular physiology: permeability of brain blood vessels; hemodynamics.
  • Neurological disorders: stroke; vascular dementia; autism.

Approaches

  • Neuroanatomy and imaging: histology for light, confocal and electron microscopy.
  • Mouse genetics: use of reporter lines and of constitutive/conditional mutations.
  • Neuropharmacology & behavior in mice: acute/chronic treatments, assessment of cognitive function.
  • Molecular biology: in vivo and in vitro analysis of signalling pathways involved in angiogenesis, neuroinflammation, and vascular remodeling.
Local: 
F-1455
Lieu: 
CERVO Research Centre
Type de séminaire: 
Conférence du Centre de recherche CERVO

Financement / Soutien / Partenaires

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