Inflamed Astrocytes: A Path to Depression Led by Menin.

Publication Type:

Journal Article

Authors:

Kaufmann, Fernanda Neutzling; Caroline Menard

Source:

Neuron, Volume 100, Issue 3, p.511-513 (2018)

Keywords:

Animals, Astrocytes, Brain, Depression, Inflammation, Mice, Neurons

Abstract:

<p>Increasing evidence supports a role for inflammation in the development of mood disorders. In this issue of Neuron, Leng et al. (2018) show that reduction of menin expression in astrocytes of stress-related brain regions exacerbates neuroinflammation, promoting the establishment of depression-like behaviors in mice.</p>