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Filtres: Author is J-P Julien  [Enlever les filtres]
2019
Renaud L, Picher-Martel V, Codron P, J-P Julien. Key role of UBQLN2 in pathogenesis of amyotrophic lateral sclerosis and frontotemporal dementia. Acta Neuropathol Commun. 2019;7(1):103.
Walker CL, Uchida A, Li Y, Trivedi N, J Fenn D, Monsma PC, Larivière RC, J-P Julien, Jung P, Brown A. Local Acceleration of Neurofilament Transport at Nodes of Ranvier. J Neurosci. 2019;39(4):663-677.
Pozzi S, Thammisetty SSa, Codron P, Rahimian R, Plourde KVa, Soucy G, Bareil C, Phaneuf D, Kriz J, Gravel C, J-P Julien. Virus-mediated delivery of antibody targeting TAR DNA-binding protein-43 mitigates associated neuropathology. J Clin Invest. 2019;129(4):1581-1595.
2018
Pozzi S, Thammisetty SSa, J-P Julien. Chronic Administration of Pimozide Fails to Attenuate Motor and Pathological Deficits in Two Mouse Models of Amyotrophic Lateral Sclerosis. Neurotherapeutics. 2018;15(3):715-727.
Paré B, Lehmann M, Beaudin M, Nordström U, Saikali S, J-P Julien, Gilthorpe JD, Marklund SL, Cashman NR, Andersen PM, Forsberg K, Dupré N, Gould P, Brännström T, Gros-Louis F. Misfolded SOD1 pathology in sporadic Amyotrophic Lateral Sclerosis. Sci Rep. 2018;8(1):14223.
Yuan A, Sershen H, Basavarajappa BS, Smiley JF, Hashim A, Bleiwas C, Berg M, Guifoyle DN, Subbanna S, Darji S, Kumar A, Rao MV, Wilson DA, J-P Julien, Javitt DC, Nixon RA. Neurofilament light interaction with GluN1 modulates neurotransmission and schizophrenia-associated behaviors. Transl Psychiatry. 2018;8(1):167.
Picher-Martel V, Renaud L, Bareil C, J-P Julien. Neuronal Expression of UBQLN2 Exacerbates TDP-43 Pathology in TDP-43 Mice through Interaction with Ubiquitin. Mol Neurobiol. 2018.
Komatsu K, Imamura K, Yamashita H, J-P Julien, Takahashi R, Inoue H. Overexpressed wild-type superoxide dismutase 1 exhibits amyotrophic lateral sclerosis-related misfolded conformation in induced pluripotent stem cell-derived spinal motor neurons. Neuroreport. 2018;29(1):25-29.
Dutta K, Patel P, J-P Julien. Protective effects of Withania somnifera extract in SOD1 mouse model of amyotrophic lateral sclerosis. Exp Neurol. 2018;309:193-204.
2017
Patten SA, Aggad D, Martinez J, Tremblay E, Petrillo J, Armstrong GAb, La Fontaine A, Maios C, Liao M, Ciura S, Wen X-Y, Rafuse V, Ichida J, Zinman L, J-P Julien, Kabashi E, Robitaille R, Korngut L, J Parker A, Drapeau P. Neuroleptics as therapeutic compounds stabilizing neuromuscular transmission in amyotrophic lateral sclerosis. JCI Insight. 2017;2(22).
Imamura K, Izumi Y, Watanabe A, Tsukita K, Woltjen K, Yamamoto T, Hotta A, Kondo T, Kitaoka S, Ohta A, Tanaka A, Watanabe D, Morita M, Takuma H, Tamaoka A, Kunath T, Wray S, Furuya H, Era T, Makioka K, Okamoto K, Fujisawa T, Nishitoh H, Homma K, Ichijo H, J-P Julien, Obata N, Hosokawa M, Akiyama H, Kaneko S, Ayaki T, Ito H, Kaji R, Takahashi R, Yamanaka S, Inoue H. The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis. Sci Transl Med. 2017;9(391).
Dutta K, Patel P, Rahimian R, Phaneuf D, J-P Julien. Withania somnifera Reverses Transactive Response DNA Binding Protein 43 Proteinopathy in a Mouse Model of Amyotrophic Lateral Sclerosis/Frontotemporal Lobar Degeneration. Neurotherapeutics. 2017;14(2):447-462.
2016
Iguchi Y, Eid L, Parent M, Soucy G, Bareil C, Riku Y, Kawai K, Takagi S, Yoshida M, Katsuno M, Sobue G, J-P Julien. Exosome secretion is a key pathway for clearance of pathological TDP-43. Brain. 2016;139(Pt 12):3187-3201.
Picher-Martel V, Valdmanis PN, Gould PV, J-P Julien, Dupré N. From animal models to human disease: a genetic approach for personalized medicine in ALS. Acta Neuropathol Commun. 2016;4(1):70.
Israeli E, Dryanovski DI, Schumacker PT, Chandel NS, Singer JD, J-P Julien, Goldman RD, Opal P. Intermediate filament aggregates cause mitochondrial dysmotility and increase energy demands in giant axonal neuropathy. Hum Mol Genet. 2016.
MacNair L, Xiao S, Miletic D, Ghani M, J-P Julien, Keith J, Zinman L, Rogaeva E, Robertson J. MTHFSD and DDX58 are novel RNA-binding proteins abnormally regulated in amyotrophic lateral sclerosis. Brain. 2016;139(Pt 1):86-100.
Yadav P, Selvaraj BT, Bender FLP, Behringer M, Moradi M, Sivadasan R, Dombert B, Blum R, Asan E, Sauer M, J-P Julien, Sendtner M. Neurofilament depletion improves microtubule dynamics via modulation of Stat3/stathmin signaling. Acta Neuropathol. 2016;132(1):93-110.
Ohta Y, Soucy G, Phaneuf D, Audet J-N, Gros-Louis F, Rouleau GA, Blasco H, Corcia P, Andersen PM, Nordin F, Yamashita T, Abe K, J-P Julien. Sex-dependent effects of chromogranin B P413L allelic variant as disease modifier in amyotrophic lateral sclerosis. Hum Mol Genet. 2016.
Ohta Y, Soucy G, Phaneuf D, Audet J-N, Gros-Louis F, Rouleau GA, Blasco H, Corcia P, Andersen PM, Nordin F, Yamashita T, Abe K, J-P Julien. Sex-dependent effects of chromogranin B P413L allelic variant as disease modifier in amyotrophic lateral sclerosis. Hum Mol Genet. 2016;25(21):4771-4786.
2015
Ghasemlou N, Chiu IM, J-P Julien, Woolf CJ. CD11b+Ly6G- myeloid cells mediate mechanical inflammatory pain hypersensitivity. Proc Natl Acad Sci USA. 2015;112(49):E6808-17.
Yuan A, Hassinger L, Rao MV, J-P Julien, Miller CCJ, Nixon RA. Dissociation of Axonal Neurofilament Content from Its Transport Rate. PLoS ONE. 2015;10(7):e0133848.
Arbour D, Tremblay E, Martineau É, J-P Julien, Robitaille R. Early and persistent abnormal decoding by glial cells at the neuromuscular junction in an ALS model. J Neurosci. 2015;35(2):688-706.
Patel P, J-P Julien, Kriz J. Early-stage treatment with Withaferin A reduces levels of misfolded superoxide dismutase 1 and extends lifespan in a mouse model of amyotrophic lateral sclerosis. Neurotherapeutics. 2015;12(1):217-33.
Yuan A, Sershen H, Basavarajappa BS, Kumar A, Hashim A, Berg M, Lee J-H, Sato Y, Rao MV, Mohan PS, Dyakin V, J-P Julien, Lee VM-, Nixon RA. Functions of neurofilaments in synapses. Mol Psychiatry. 2015;20(8):915.
Correia ASo, Patel P, Dutta K, J-P Julien. Inflammation Induces TDP-43 Mislocalization and Aggregation. PLoS ONE. 2015;10(10):e0140248.

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