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Filtres: Author is J-P Julien  [Enlever les filtres]
2020
Mishra PS, Boutej H, Soucy G, Bareil C, Kumar S, Picher-Martel V, et al. Transmission of ALS pathogenesis by the cerebrospinal fluid. Acta neuropathologica communications. 2020;8(1):65.
2019
Renaud L, Picher-Martel V, Codron P, J-P Julien. Key role of UBQLN2 in pathogenesis of amyotrophic lateral sclerosis and frontotemporal dementia. Acta Neuropathol Commun. 2019;7(1):103.
Walker CL, Uchida A, Li Y, Trivedi N, J Fenn D, Monsma PC, et al. Local Acceleration of Neurofilament Transport at Nodes of Ranvier. J Neurosci. 2019;39(4):663-677.
Pozzi S, Thammisetty SS, Codron P, Rahimian R, Plourde KV, Soucy G, et al. Virus-mediated delivery of antibody targeting TAR DNA-binding protein-43 mitigates associated neuropathology. J Clin Invest. 2019;129(4):1581-1595.
2018
Pozzi S, Thammisetty SS, J-P Julien. Chronic Administration of Pimozide Fails to Attenuate Motor and Pathological Deficits in Two Mouse Models of Amyotrophic Lateral Sclerosis. Neurotherapeutics. 2018;15(3):715-727.
Paré B, Lehmann M, Beaudin M, Nordström U, Saikali S, J-P Julien, et al. Misfolded SOD1 pathology in sporadic Amyotrophic Lateral Sclerosis. Sci Rep. 2018;8(1):14223.
Yuan A, Sershen H, Basavarajappa BS, Smiley JF, Hashim A, Bleiwas C, et al. Neurofilament light interaction with GluN1 modulates neurotransmission and schizophrenia-associated behaviors. Transl Psychiatry. 2018;8(1):167.
Picher-Martel V, Renaud L, Bareil C, J-P Julien. Neuronal Expression of UBQLN2 Exacerbates TDP-43 Pathology in TDP-43 Mice through Interaction with Ubiquitin. Mol Neurobiol. 2018.
Komatsu K, Imamura K, Yamashita H, J-P Julien, Takahashi R, Inoue H. Overexpressed wild-type superoxide dismutase 1 exhibits amyotrophic lateral sclerosis-related misfolded conformation in induced pluripotent stem cell-derived spinal motor neurons. Neuroreport. 2018;29(1):25-29.
Dutta K, Patel P, J-P Julien. Protective effects of Withania somnifera extract in SOD1 mouse model of amyotrophic lateral sclerosis. Exp Neurol. 2018;309:193-204.
2017
Patten SA, Aggad D, Martinez J, Tremblay E, Petrillo J, Armstrong GA, et al. Neuroleptics as therapeutic compounds stabilizing neuromuscular transmission in amyotrophic lateral sclerosis. JCI Insight. 2017;2(22).
Imamura K, Izumi Y, Watanabe A, Tsukita K, Woltjen K, Yamamoto T, et al. The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis. Sci Transl Med. 2017;9(391).
Dutta K, Patel P, Rahimian R, Phaneuf D, J-P Julien. Withania somnifera Reverses Transactive Response DNA Binding Protein 43 Proteinopathy in a Mouse Model of Amyotrophic Lateral Sclerosis/Frontotemporal Lobar Degeneration. Neurotherapeutics. 2017;14(2):447-462.
2016
Iguchi Y, Eid L, Parent M, Soucy G, Bareil C, Riku Y, et al. Exosome secretion is a key pathway for clearance of pathological TDP-43. Brain. 2016;139(Pt 12):3187-3201.
Picher-Martel V, Valdmanis PN, Gould PV, J-P Julien, Dupré N. From animal models to human disease: a genetic approach for personalized medicine in ALS. Acta Neuropathol Commun. 2016;4(1):70.
Israeli E, Dryanovski DI, Schumacker PT, Chandel NS, Singer JD, J-P Julien, et al. Intermediate filament aggregates cause mitochondrial dysmotility and increase energy demands in giant axonal neuropathy. Hum Mol Genet. 2016.
MacNair L, Xiao S, Miletic D, Ghani M, J-P Julien, Keith J, et al. MTHFSD and DDX58 are novel RNA-binding proteins abnormally regulated in amyotrophic lateral sclerosis. Brain. 2016;139(Pt 1):86-100.
Yadav P, Selvaraj BT, Bender FL, Behringer M, Moradi M, Sivadasan R, et al. Neurofilament depletion improves microtubule dynamics via modulation of Stat3/stathmin signaling. Acta Neuropathol. 2016;132(1):93-110.
Ohta Y, Soucy G, Phaneuf D, Audet J-, Gros-Louis F, Rouleau GA, et al. Sex-dependent effects of chromogranin B P413L allelic variant as disease modifier in amyotrophic lateral sclerosis. Hum Mol Genet. 2016.
Ohta Y, Soucy G, Phaneuf D, Audet J-, Gros-Louis F, Rouleau GA, et al. Sex-dependent effects of chromogranin B P413L allelic variant as disease modifier in amyotrophic lateral sclerosis. Hum Mol Genet. 2016;25(21):4771-4786.
2015
Ghasemlou N, Chiu IM, J-P Julien, Woolf CJ. CD11b+Ly6G- myeloid cells mediate mechanical inflammatory pain hypersensitivity. Proc Natl Acad Sci USA. 2015;112(49):E6808-17.
Yuan A, Hassinger L, Rao MV, J-P Julien, Miller CC, Nixon RA. Dissociation of Axonal Neurofilament Content from Its Transport Rate. PLoS ONE. 2015;10(7):e0133848.
Arbour D, Tremblay E, Martineau É, J-P Julien, Robitaille R. Early and persistent abnormal decoding by glial cells at the neuromuscular junction in an ALS model. J Neurosci. 2015;35(2):688-706.
Patel P, J-P Julien, Kriz J. Early-stage treatment with Withaferin A reduces levels of misfolded superoxide dismutase 1 and extends lifespan in a mouse model of amyotrophic lateral sclerosis. Neurotherapeutics. 2015;12(1):217-33.
Yuan A, Sershen H, Basavarajappa BS, Kumar A, Hashim A, Berg M, et al. Functions of neurofilaments in synapses. Mol Psychiatry. 2015;20(8):915.

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