Publications
Export 140 results:
Filtres: Author is Mohamed Chahine [Enlever les filtres]
, « Na1.5 knockout in iPSCs: a novel approach to study Na1.5 variants in a human cardiomyocyte environment. », Sci Rep, vol. 11, nᵒ 1, p. 17168, 2021.
, « Novel G1481V and Q1491H SCN5A Mutations Linked to Long QT Syndrome Destabilize the Nav1.5 Inactivation State. », CJC Open, vol. 3, nᵒ 3, p. 256-266, 2021.
, « R1617Q epilepsy mutation slows Na 1.6 sodium channel inactivation and increases the persistent current and neuronal firing. », J Physiol, vol. 599, nᵒ 5, p. 1651-1664, 2021.
, « Exome Sequencing Implicates Impaired GABA Signaling and Neuronal Ion Transport in Trigeminal Neuralgia. », iScience, vol. 23, nᵒ 10, p. 101552, 2020.
, « Voltage-gated sodium channels from the bees Apis mellifera and Bombus terrestris are differentially modulated by pyrethroid insecticides. », Sci Rep, vol. 9, nᵒ 1, p. 1078, 2019.
, « A204E mutation in Na1.4 DIS3 exerts gain- and loss-of-function effects that lead to periodic paralysis combining hyper- with hypo-kalaemic signs. », Sci Rep, vol. 8, nᵒ 1, p. 16681, 2018.
, « Interleukin-6 inhibition of hERG underlies risk for acquired long QT in cardiac and systemic inflammation. », PLoS One, vol. 13, nᵒ 12, p. e0208321, 2018.
, « A leaky voltage sensor domain of cardiac sodium channels causes arrhythmias associated with dilated cardiomyopathy. », Sci Rep, vol. 8, nᵒ 1, p. 13804, 2018.
, « A New Cardiac Channelopathy: From Clinical Phenotypes to Molecular Mechanisms Associated With Na1.5 Gating Pores. », Front Cardiovasc Med, vol. 5, p. 139, 2018.
, « Biophysical characterization of the Varroa destructor NaV1 sodium channel and its affinity for τ-fluvalinate insecticide. », FASEB J, vol. 31, nᵒ 7, p. 3066-3071, 2017.
, « Biophysical, Molecular, and Pharmacological Characterization of Voltage-Dependent Sodium Channels From Induced Pluripotent Stem Cell-Derived Cardiomyocytes. », Can J Cardiol, vol. 33, nᵒ 2, p. 269-278, 2017.
, « Induced pluripotent stem-cell-derived cardiomyocytes: cardiac applications, opportunities, and challenges. », Can J Physiol Pharmacol, vol. 95, nᵒ 10, p. 1108-1116, 2017.
, « Mechanisms of Drug Binding to Voltage-Gated Sodium Channels. », Handb Exp Pharmacol, 2017.
, « Metaflumizone inhibits the honeybee NaV 1 channel by targeting recovery from slow inactivation. », FEBS Lett, 2017.
, « Regulation of Cardiac Voltage-Gated Sodium Channel by Kinases: Roles of Protein Kinases A and C. », Handb Exp Pharmacol, 2017.
, « Biophysical characterization of the honeybee DSC1 orthologue reveals a novel voltage-dependent Ca2+ channel subfamily: CaV4. », J Gen Physiol, vol. 148, nᵒ 2, p. 133-45, 2016.
, « Editorial: Recent Advances in Voltage-Gated Sodium Channels, their Pharmacology and Related Diseases. », Front Pharmacol, vol. 7, p. 20, 2016.
, « Induction of autoimmune response to the extracellular loop of the HERG channel pore induces QTc prolongation in guinea-pigs. », J Physiol, vol. 594, nᵒ 21, p. 6175-6187, 2016.
, « A recessive Nav1.4 mutation underlies congenital myasthenic syndrome with periodic paralysis. », Neurology, vol. 86, nᵒ 2, p. 161-9, 2016.
, « Characterization of the honeybee AmNaV1 channel and tools to assess the toxicity of insecticides. », Sci Rep, vol. 5, p. 12475, 2015.
, « Differential modulation of Nav1.7 and Nav1.8 channels by antidepressant drugs. », Eur J Pharmacol, vol. 764, p. 395-403, 2015.
, « Effects of amlodipine and perindoprilate on the structure and function of mitochondria in ventricular cardiomyocytes during ischemia-reperfusion in the pig. », Fundam Clin Pharmacol, vol. 29, nᵒ 1, p. 21-30, 2015.
, « Gating pore current is a novel biophysical defect of Nav1.5 mutations associated with unusual cardiac arrhythmias and dilation. », Future Cardiol, vol. 11, nᵒ 3, p. 287-91, 2015.
, « Gating pore currents, a new pathological mechanism underlying cardiac arrhythmias associated with dilated cardiomyopathy. », Channels (Austin), vol. 9, nᵒ 3, p. 139-44, 2015.
, « Gating pore currents are defects in common with two Nav1.5 mutations in patients with mixed arrhythmias and dilated cardiomyopathy. », J Gen Physiol, vol. 145, nᵒ 2, p. 93-106, 2015.
