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Publications

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Filtres: Author is J-P Julien  [Enlever les filtres]
2018
Walker CL, Uchida A, Li Y, Trivedi N, J Fenn D, Monsma PC, Larivière RC, J-P Julien, Jung P, Brown A. Local acceleration of neurofilament transport at nodes of Ranvier. J Neurosci. 2018.
Picher-Martel V, Renaud L, Bareil C, J-P Julien. Neuronal Expression of UBQLN2 Exacerbates TDP-43 Pathology in TDP-43 Mice through Interaction with Ubiquitin. Mol Neurobiol. 2018.
Paré B, Lehmann M, Beaudin M, Nordström U, Saikali S, J-P Julien, Gilthorpe JD, Marklund SL, Cashman NR, Andersen PM, Forsberg K, Dupré N, Gould P, Brännström T, Gros-Louis F. Misfolded SOD1 pathology in sporadic Amyotrophic Lateral Sclerosis. Sci Rep. 2018;8(1):14223.
Dutta K, Patel P, J-P Julien. Protective effects of Withania somnifera extract in SOD1 mouse model of amyotrophic lateral sclerosis. Exp Neurol. 2018;309:193-204.
Yuan A, Sershen H, Basavarajappa BS, Smiley JF, Hashim A, Bleiwas C, Berg M, Guifoyle DN, Subbanna S, Darji S, Kumar A, Rao MV, Wilson DA, J-P Julien, Javitt DC, Nixon RA. Neurofilament light interaction with GluN1 modulates neurotransmission and schizophrenia-associated behaviors. Transl Psychiatry. 2018;8(1):167.
Pozzi S, Thammisetty SS, J-P Julien. Chronic Administration of Pimozide Fails to Attenuate Motor and Pathological Deficits in Two Mouse Models of Amyotrophic Lateral Sclerosis. Neurotherapeutics. 2018;15(3):715-727.
Komatsu K, Imamura K, Yamashita H, J-P Julien, Takahashi R, Inoue H. Overexpressed wild-type superoxide dismutase 1 exhibits amyotrophic lateral sclerosis-related misfolded conformation in induced pluripotent stem cell-derived spinal motor neurons. Neuroreport. 2018;29(1):25-29.
2016
Ohta Y, Soucy G, Phaneuf D, Audet J-, Gros-Louis F, Rouleau GA, Blasco H, Corcia P, Andersen PM, Nordin F, Yamashita T, Abe K, J-P Julien. Sex-dependent effects of chromogranin B P413L allelic variant as disease modifier in amyotrophic lateral sclerosis. Hum Mol Genet. 2016;25(21):4771-4786.
MacNair L, Xiao S, Miletic D, Ghani M, J-P Julien, Keith J, Zinman L, Rogaeva E, Robertson J. MTHFSD and DDX58 are novel RNA-binding proteins abnormally regulated in amyotrophic lateral sclerosis. Brain. 2016;139(Pt 1):86-100.
Israeli E, Dryanovski DI, Schumacker PT, Chandel NS, Singer JD, J-P Julien, Goldman RD, Opal P. Intermediate filament aggregates cause mitochondrial dysmotility and increase energy demands in giant axonal neuropathy. Hum Mol Genet. 2016.
Yadav P, Selvaraj BT, Bender FL, Behringer M, Moradi M, Sivadasan R, Dombert B, Blum R, Asan E, Sauer M, J-P Julien, Sendtner M. Neurofilament depletion improves microtubule dynamics via modulation of Stat3/stathmin signaling. Acta Neuropathol. 2016;132(1):93-110.
Iguchi Y, Eid L, Parent M, Soucy G, Bareil C, Riku Y, Kawai K, Takagi S, Yoshida M, Katsuno M, Sobue G, J-P Julien. Exosome secretion is a key pathway for clearance of pathological TDP-43. Brain. 2016;139(Pt 12):3187-3201.
Ohta Y, Soucy G, Phaneuf D, Audet J-, Gros-Louis F, Rouleau GA, Blasco H, Corcia P, Andersen PM, Nordin F, Yamashita T, Abe K, J-P Julien. Sex-dependent effects of chromogranin B P413L allelic variant as disease modifier in amyotrophic lateral sclerosis. Hum Mol Genet. 2016.
Picher-Martel V, Valdmanis PN, Gould PV, J-P Julien, Dupré N. From animal models to human disease: a genetic approach for personalized medicine in ALS. Acta Neuropathol Commun. 2016;4(1):70.
2015
Patel P, J-P Julien, Kriz J. Early-stage treatment with Withaferin A reduces levels of misfolded superoxide dismutase 1 and extends lifespan in a mouse model of amyotrophic lateral sclerosis. Neurotherapeutics. 2015;12(1):217-33.
Arbour D, Tremblay E, Martineau É, J-P Julien, Robitaille R. Early and persistent abnormal decoding by glial cells at the neuromuscular junction in an ALS model. J Neurosci. 2015;35(2):688-706.
Yuan A, Sershen H, Basavarajappa BS, Kumar A, Hashim A, Berg M, Lee J-, Sato Y, Rao MV, Mohan PS, Dyakin V, J-P Julien, Lee VM, Nixon RA. Neurofilament subunits are integral components of synapses and modulate neurotransmission and behavior in vivo. Mol Psychiatry. 2015;20(8):986-94.
Froud KE, Wong AC, Cederholm JM, Klugmann M, Sandow SL, J-P Julien, Ryan AF, Housley GD. Type II spiral ganglion afferent neurons drive medial olivocochlear reflex suppression of the cochlear amplifier. Nat Commun. 2015;6:7115.
Yuan A, Sershen H, Basavarajappa BS, Kumar A, Hashim A, Berg M, Lee J-, Sato Y, Rao MV, Mohan PS, Dyakin V, J-P Julien, Lee VM, Nixon RA. Functions of neurofilaments in synapses. Mol Psychiatry. 2015;20(8):915.
Yuan A, Hassinger L, Rao MV, J-P Julien, Miller CC, Nixon RA. Dissociation of Axonal Neurofilament Content from Its Transport Rate. PLoS ONE. 2015;10(7):e0133848.
Correia AS, Patel P, Dutta K, J-P Julien. Inflammation Induces TDP-43 Mislocalization and Aggregation. PLoS ONE. 2015;10(10):e0140248.
Picher-Martel V, Dutta K, Phaneuf D, Sobue G, J-P Julien. Ubiquilin-2 drives NF-κB activity and cytosolic TDP-43 aggregation in neuronal cells. Mol Brain. 2015;8(1):71.

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