Publications
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Filtres: Keyword is Superoxide Dismutase [Enlever les filtres]
, « Adeno-associated virus-mediated delivery of a recombinant single-chain antibody against misfolded superoxide dismutase for treatment of amyotrophic lateral sclerosis. », Mol Ther, vol. 22, nᵒ 3, p. 498-510, 2014.
, « Mitochondrial damage revealed by immunoselection for ALS-linked misfolded SOD1. », Hum Mol Genet, vol. 22, nᵒ 19, p. 3947-59, 2013.
, « Neuroprotection through excitability and mTOR required in ALS motoneurons to delay disease and extend survival. », Neuron, vol. 80, nᵒ 1, p. 80-96, 2013.
, « Ablation of proliferating cells in the CNS exacerbates motor neuron disease caused by mutant superoxide dismutase. », PLoS One, vol. 7, nᵒ 4, p. e34932, 2012.
, « Localization of a toxic form of superoxide dismutase 1 protein to pathologically affected tissues in familial ALS. », Proc Natl Acad Sci U S A, vol. 109, nᵒ 14, p. 5505-10, 2012.
, « Methylene blue administration fails to confer neuroprotection in two amyotrophic lateral sclerosis mouse models. », Neuroscience, vol. 209, p. 136-43, 2012.
, « ALS pathogenesis: recent insights from genetics and mouse models. », Prog Neuropsychopharmacol Biol Psychiatry, vol. 35, nᵒ 2, p. 363-9, 2011.
, « Misfolded SOD1 associated with motor neuron mitochondria alters mitochondrial shape and distribution prior to clinical onset. », PLoS One, vol. 6, nᵒ 7, p. e22031, 2011.
, « Treatment with minocycline after disease onset alters astrocyte reactivity and increases microgliosis in SOD1 mutant mice. », Exp Neurol, vol. 228, nᵒ 1, p. 69-79, 2011.
, « Extracellular mutant SOD1 induces microglial-mediated motoneuron injury. », Glia, vol. 58, nᵒ 2, p. 231-43, 2010.
, « Induction of protective immunity by vaccination with wild-type apo superoxide dismutase 1 in mutant SOD1 transgenic mice. », J Neuropathol Exp Neurol, vol. 69, nᵒ 10, p. 1044-56, 2010.
, « Intracerebroventricular infusion of monoclonal antibody or its derived Fab fragment against misfolded forms of SOD1 mutant delays mortality in a mouse model of ALS. », J Neurochem, vol. 113, nᵒ 5, p. 1188-99, 2010.
, « Neuronal over-expression of chromogranin A accelerates disease onset in a mouse model of ALS. », J Neurochem, vol. 115, nᵒ 5, p. 1102-11, 2010.
, « Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS. », Nat Neurosci, vol. 13, nᵒ 11, p. 1396-403, 2010.
, « Wild-type human SOD1 overexpression does not accelerate motor neuron disease in mice expressing murine Sod1 G86R. », Neurobiol Dis, vol. 40, nᵒ 1, p. 245-50, 2010.
, « Live imaging of amyotrophic lateral sclerosis pathogenesis: disease onset is characterized by marked induction of GFAP in Schwann cells. », Glia, vol. 57, nᵒ 10, p. 1130-42, 2009.
, « Macrophage colony stimulating factor (M-CSF) exacerbates ALS disease in a mouse model through altered responses of microglia expressing mutant superoxide dismutase. », Exp Neurol, vol. 220, nᵒ 2, p. 267-75, 2009.
, « A novel function for fragile X mental retardation protein in translational activation. », PLoS Biol, vol. 7, nᵒ 1, p. e16, 2009.
, « Ablation of proliferating microglia does not affect motor neuron degeneration in amyotrophic lateral sclerosis caused by mutant superoxide dismutase. », J Neurosci, vol. 28, nᵒ 41, p. 10234-44, 2008.
, « The endoplasmic reticulum-Golgi pathway is a target for translocation and aggregation of mutant superoxide dismutase linked to ALS. », FASEB J, vol. 22, nᵒ 7, p. 2476-87, 2008.
, « Therapeutic effects of immunization with mutant superoxide dismutase in mice models of amyotrophic lateral sclerosis. », Proc Natl Acad Sci U S A, vol. 104, nᵒ 7, p. 2495-500, 2007.
, « Therapeutic immunization with a glatiramer acetate derivative does not alter survival in G93A and G37R SOD1 mouse models of familial ALS. », Neurobiol Dis, vol. 26, nᵒ 1, p. 146-52, 2007.
, « Wild-type superoxide dismutase acquires binding and toxic properties of ALS-linked mutant forms through oxidation. », J Neurochem, vol. 102, nᵒ 1, p. 170-8, 2007.
, « Absence of tumor necrosis factor-alpha does not affect motor neuron disease caused by superoxide dismutase 1 mutations. », J Neurosci, vol. 26, nᵒ 44, p. 11397-402, 2006.
, « Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis. », Nat Neurosci, vol. 9, nᵒ 1, p. 108-18, 2006.
