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Filtres: Author is Mohamed Chahine  [Enlever les filtres]
2014
A. Moreau, Gosselin-Badaroudine, P., et Chahine, M., « Biophysics, pathophysiology, and pharmacology of ion channel gating pores. », Front Pharmacol, vol. 5, p. 53, 2014.
O. Thériault et Chahine, M., « Correlation of the electrophysiological profiles and sodium channel transcripts of individual rat dorsal root ganglia neurons. », Front Cell Neurosci, vol. 8, p. 285, 2014.
H. Poulin, Bruhova, I., Timour, Q., Thériault, O., Beaulieu, J. - M., Frassati, D., et Chahine, M., « Fluoxetine blocks Nav1.5 channels via a mechanism similar to that of class 1 antiarrhythmics. », Mol Pharmacol, vol. 86, nᵒ 4, p. 378-89, 2014.
O. Thériault, Poulin, H., Sculptoreanu, A., de Groat, W. C., O'Leary, M. E., et Chahine, M., « Modulation of peripheral Na(+) channels and neuronal firing by n-butyl-p-aminobenzoate. », Eur J Pharmacol, vol. 727, p. 158-66, 2014.
A. Moreau, Gosselin-Badaroudine, P., et Chahine, M., « Molecular biology and biophysical properties of ion channel gating pores. », Q Rev Biophys, vol. 47, nᵒ 4, p. 364-88, 2014.
T. Pambrun, Mercier, A., Chatelier, A., Patri, S., Schott, J. - J., Le Scouarnec, S., Chahine, M., Degand, B., et Bois, P., « Myotonic dystrophy type 1 mimics and exacerbates Brugada phenotype induced by Nav1.5 sodium channel loss-of-function mutation. », Heart Rhythm, vol. 11, nᵒ 8, p. 1393-400, 2014.
P. Gosselin-Badaroudine, Moreau, A., et Chahine, M., « Nav 1.5 mutations linked to dilated cardiomyopathy phenotypes: Is the gating pore current the missing link? », Channels (Austin), vol. 8, nᵒ 1, p. 90-4, 2014.
A. Kadala, Charreton, M., Jakob, I., Cens, T., Rousset, M., Chahine, M., Le Conte, Y., Charnet, P., et Collet, C., « Pyrethroids differentially alter voltage-gated sodium channels from the honeybee central olfactory neurons. », PLoS One, vol. 9, nᵒ 11, p. e112194, 2014.
O. Thériault, Poulin, H., Thomas, G. R., Friesen, A. D., Al-Shaqha, W. A., et Chahine, M., « Pyridoxal-5'-phosphate (MC-1), a vitamin B6 derivative, inhibits expressed P2X receptors. », Can J Physiol Pharmacol, vol. 92, nᵒ 3, p. 189-96, 2014.
M. Chahine et O'Leary, M. E., « Regulation/modulation of sensory neuron sodium channels. », Handb Exp Pharmacol, vol. 221, p. 111-35, 2014.
A. Mechakra, Vincent, Y., Chevalier, P., Millat, G., Ficker, E., Jastrzebski, M., Poulin, H., Pouliot, V., Chahine, M., et Christé, G., « The variant hERG/R148W associated with LQTS is a mutation that reduces current density on co-expression with the WT. », Gene, vol. 536, nᵒ 2, p. 348-56, 2014.
2012
J. Zhao, Dupré, N., Puymirat, J., et Chahine, M., « Biophysical characterization of M1476I, a sodium channel founder mutation associated with cold-induced myotonia in French Canadians. », J Physiol, vol. 590, nᵒ 11, p. 2629-44, 2012.
S. - N. Chiu, Wu, M. - H., Su, M. - J., Wang, J. - K., Lin, M. - T., Chang, C. - C., Hsu, H. - W., Shen, C. - T., Thériault, O., et Chahine, M., « Coexisting mutations/polymorphisms of the long QT syndrome genes in patients with repaired Tetralogy of Fallot are associated with the risks of life-threatening events. », Hum Genet, vol. 131, nᵒ 8, p. 1295-304, 2012.
C. Ho, Zhao, J., Malinowski, S., Chahine, M., et O'Leary, M. E., « Differential expression of sodium channel β subunits in dorsal root ganglion sensory neurons. », J Biol Chem, vol. 287, nᵒ 18, p. 15044-53, 2012.
A. Chatelier, Mercier, A., Tremblier, B., Thériault, O., Moubarak, M., Benamer, N., Corbi, P., Bois, P., Chahine, M., et Faivre, J. François, « A distinct de novo expression of Nav1.5 sodium channels in human atrial fibroblasts differentiated into myofibroblasts. », J Physiol, vol. 590, nᵒ 17, p. 4307-19, 2012.
P. Gosselin-Badaroudine, Delemotte, L., Moreau, A., Klein, M. L., et Chahine, M., « Gating pore currents and the resting state of Nav1.4 voltage sensor domains. », Proc Natl Acad Sci U S A, vol. 109, nᵒ 47, p. 19250-5, 2012.
A. Moreau, Keller, D. I., Huang, H., Fressart, V., Schmied, C., Timour, Q., et Chahine, M., « Mexiletine differentially restores the trafficking defects caused by two brugada syndrome mutations. », Front Pharmacol, vol. 3, p. 62, 2012.
P. Gosselin-Badaroudine, Keller, D. I., Huang, H., Pouliot, V., Chatelier, A., Osswald, S., Brink, M., et Chahine, M., « A proton leak current through the cardiac sodium channel is linked to mixed arrhythmia and the dilated cardiomyopathy phenotype. », PLoS One, vol. 7, nᵒ 5, p. e38331, 2012.

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