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Publications

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Filtres: Author is Mohamed Chahine  [Enlever les filtres]
2014
Moreau A, Gosselin-Badaroudine P, Chahine M. Biophysics, pathophysiology, and pharmacology of ion channel gating pores. Front Pharmacol. 2014;5:53.
Thériault O, Chahine M. Correlation of the electrophysiological profiles and sodium channel transcripts of individual rat dorsal root ganglia neurons. Front Cell Neurosci. 2014;8:285.
Poulin H, Bruhova I, Timour Q, Thériault O, Beaulieu J-M, Frassati D, Chahine M. Fluoxetine blocks Nav1.5 channels via a mechanism similar to that of class 1 antiarrhythmics. Mol Pharmacol. 2014;86(4):378-89.
Thériault O, Poulin H, Sculptoreanu A, de Groat WC, O'Leary ME, Chahine M. Modulation of peripheral Na(+) channels and neuronal firing by n-butyl-p-aminobenzoate. Eur J Pharmacol. 2014;727:158-66.
Moreau A, Gosselin-Badaroudine P, Chahine M. Molecular biology and biophysical properties of ion channel gating pores. Q Rev Biophys. 2014;47(4):364-88.
Pambrun T, Mercier A, Chatelier A, Patri S, Schott J-J, Le Scouarnec S, Chahine M, Degand B, Bois P. Myotonic dystrophy type 1 mimics and exacerbates Brugada phenotype induced by Nav1.5 sodium channel loss-of-function mutation. Heart Rhythm. 2014;11(8):1393-400.
Gosselin-Badaroudine P, Moreau A, Chahine M. Nav 1.5 mutations linked to dilated cardiomyopathy phenotypes: Is the gating pore current the missing link? Channels (Austin). 2014;8(1):90-4.
Kadala A, Charreton M, Jakob I, Cens T, Rousset M, Chahine M, Le Conte Y, Charnet P, Collet C. Pyrethroids differentially alter voltage-gated sodium channels from the honeybee central olfactory neurons. PLoS ONE. 2014;9(11):e112194.
Thériault O, Poulin H, Thomas GR, Friesen AD, Al-Shaqha WA, Chahine M. Pyridoxal-5'-phosphate (MC-1), a vitamin B6 derivative, inhibits expressed P2X receptors. Can J Physiol Pharmacol. 2014;92(3):189-96.
Chahine M, O'Leary ME. Regulation/modulation of sensory neuron sodium channels. Handb Exp Pharmacol. 2014;221:111-35.
Mechakra A, Vincent Y, Chevalier P, Millat G, Ficker E, Jastrzebski M, Poulin H, Pouliot V, Chahine M, Christé G. The variant hERG/R148W associated with LQTS is a mutation that reduces current density on co-expression with the WT. Gene. 2014;536(2):348-56.
2012
Zhao J, Dupré N, Puymirat J, Chahine M. Biophysical characterization of M1476I, a sodium channel founder mutation associated with cold-induced myotonia in French Canadians. J Physiol (Lond). 2012;590(11):2629-44.
Chiu S-N, Wu M-H, Su M-J, Wang J-K, Lin M-T, Chang C-C, Hsu H-W, Shen C-T, Thériault O, Chahine M. Coexisting mutations/polymorphisms of the long QT syndrome genes in patients with repaired Tetralogy of Fallot are associated with the risks of life-threatening events. Hum Genet. 2012;131(8):1295-304.
Ho C, Zhao J, Malinowski S, Chahine M, O'Leary ME. Differential expression of sodium channel β subunits in dorsal root ganglion sensory neurons. J Biol Chem. 2012;287(18):15044-53.
Chatelier A, Mercier A, Tremblier B, Thériault O, Moubarak M, Benamer N, Corbi P, Bois P, Chahine M, Faivre JFr. A distinct de novo expression of Nav1.5 sodium channels in human atrial fibroblasts differentiated into myofibroblasts. J Physiol (Lond). 2012;590(17):4307-19.
Gosselin-Badaroudine P, Delemotte L, Moreau A, Klein ML, Chahine M. Gating pore currents and the resting state of Nav1.4 voltage sensor domains. Proc Natl Acad Sci USA. 2012;109(47):19250-5.
Moreau A, Keller DI, Huang H, Fressart V, Schmied C, Timour Q, Chahine M. Mexiletine differentially restores the trafficking defects caused by two brugada syndrome mutations. Front Pharmacol. 2012;3:62.
Gosselin-Badaroudine P, Keller DI, Huang H, Pouliot V, Chatelier A, Osswald S, Brink M, Chahine M. A proton leak current through the cardiac sodium channel is linked to mixed arrhythmia and the dilated cardiomyopathy phenotype. PLoS ONE. 2012;7(5):e38331.
Timour Q, Frassati D, Descotes J, Chevalier P, Christé G, Chahine M. Sudden death of cardiac origin and psychotropic drugs. Front Pharmacol. 2012;3:76.

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