Export 140 results:
Filtres: Author is Mohamed Chahine  [Enlever les filtres]
P. Gosselin-Badaroudine, Delemotte, L., Moreau, A., Klein, M. L., et Chahine, M., « Gating pore currents and the resting state of Nav1.4 voltage sensor domains. », Proc Natl Acad Sci U S A, vol. 109, nᵒ 47, p. 19250-5, 2012.
A. Moreau, Keller, D. I., Huang, H., Fressart, V., Schmied, C., Timour, Q., et Chahine, M., « Mexiletine differentially restores the trafficking defects caused by two brugada syndrome mutations. », Front Pharmacol, vol. 3, p. 62, 2012.
P. Gosselin-Badaroudine, Keller, D. I., Huang, H., Pouliot, V., Chatelier, A., Osswald, S., Brink, M., et Chahine, M., « A proton leak current through the cardiac sodium channel is linked to mixed arrhythmia and the dilated cardiomyopathy phenotype. », PLoS One, vol. 7, nᵒ 5, p. e38331, 2012.
Q. Timour, Frassati, D., Descotes, J., Chevalier, P., Christé, G., et Chahine, M., « Sudden death of cardiac origin and psychotropic drugs. », Front Pharmacol, vol. 3, p. 76, 2012.
A. Mercier, Clément, R., Harnois, T., Bourmeyster, N., Faivre, J. - F., Findlay, I., Chahine, M., Bois, P., et Chatelier, A., « The β1-subunit of Na(v)1.5 cardiac sodium channel is required for a dominant negative effect through α-α interaction. », PLoS One, vol. 7, nᵒ 11, p. e48690, 2012.
H. Huang, Millat, G., Rodriguez-Lafrasse, C., Rousson, R., Kugener, B., Chevalier, P., et Chahine, M., « Biophysical characterization of a new SCN5A mutation S1333Y in a SIDS infant linked to long QT syndrome. », FEBS Lett, vol. 583, nᵒ 5, p. 890-6, 2009.
M. Chahine, « Cardiac metabolic state and Brugada syndrome: a link revealed. », Circ Res, vol. 105, nᵒ 8, p. 721-3, 2009.
D. I. Keller, Grenier, J., Christé, G., Dubouloz, F., Osswald, S., Brink, M., Ficker, E., et Chahine, M., « Characterization of novel KCNH2 mutations in type 2 long QT syndrome manifesting as seizures. », Can J Cardiol, vol. 25, nᵒ 8, p. 455-62, 2009.
G. Millat, Kugener, B., Chevalier, P., Chahine, M., Huang, H., Malicier, D., Rodriguez-Lafrasse, C., et Rousson, R., « Contribution of long-QT syndrome genetic variants in sudden infant death syndrome. », Pediatr Cardiol, vol. 30, nᵒ 4, p. 502-9, 2009.
Q. Li, Huang, H., Liu, G., Lam, K., Rutberg, J., Green, M. S., Birnie, D. H., Lemery, R., Chahine, M., et Gollob, M. H., « Gain-of-function mutation of Nav1.5 in atrial fibrillation enhances cellular excitability and lowers the threshold for action potential firing. », Biochem Biophys Res Commun, vol. 380, nᵒ 1, p. 132-7, 2009.
O. Ramadan, Qu, Y., Wadgaonkar, R., Baroudi, G., Karnabi, E., Chahine, M., et Boutjdir, M., « Phosphorylation of the consensus sites of protein kinase A on alpha1D L-type calcium channel. », J Biol Chem, vol. 284, nᵒ 8, p. 5042-9, 2009.
A. Chatelier, Dahllund, L., Eriksson, A., Krupp, J., et Chahine, M., « Biophysical properties of human Na v1.7 splice variants and their regulation by protein kinase A. », J Neurophysiol, vol. 99, nᵒ 5, p. 2241-50, 2008.
G. Christé, Chahine, M., Chevalier, P., et Pásek, M., « Changes in action potentials and intracellular ionic homeostasis in a ventricular cell model related to a persistent sodium current in SCN5A mutations underlying LQT3. », Prog Biophys Mol Biol, vol. 96, nᵒ 1-3, p. 281-93, 2008.
M. Israil Hossain, Iwasaki, H., Okochi, Y., Chahine, M., Higashijima, S., Nagayama, K., et Okamura, Y., « Enzyme domain affects the movement of the voltage sensor in ascidian and zebrafish voltage-sensing phosphatases. », J Biol Chem, vol. 283, nᵒ 26, p. 18248-59, 2008.
M. - T. Lin, Wu, M. - H., Chang, C. - C., Chiu, S. - N., Thériault, O., Huang, H., Christé, G., Ficker, E., et Chahine, M., « In utero onset of long QT syndrome with atrioventricular block and spontaneous or lidocaine-induced ventricular tachycardia: compound effects of hERG pore region mutation and SCN5A N-terminus variant. », Heart Rhythm, vol. 5, nᵒ 11, p. 1567-74, 2008.
G. Christé, Thériault, O., Chahine, M., Millat, G., Rodriguez-Lafrasse, C., Rousson, R., Deschênes, I., Ficker, E., et Chevalier, P., « A new C-terminal hERG mutation A915fs+47X associated with symptomatic LQT2 and auditory-trigger syncope. », Heart Rhythm, vol. 5, nᵒ 11, p. 1577-86, 2008.
I. Six, Hermida, J. - S., Huang, H., Gouas, L., Fressart, V., Benammar, N., Hainque, B., Denjoy, I., Chahine, M., et Guicheney, P., « The occurrence of Brugada syndrome and isolated cardiac conductive disease in the same family could be due to a single SCN5A mutation or to the accidental association of both diseases. », Europace, vol. 10, nᵒ 1, p. 79-85, 2008.

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