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Filtres: Author is Moreau, Adrien [Enlever les filtres]
A leaky voltage sensor domain of cardiac sodium channels causes arrhythmias associated with dilated cardiomyopathy. Sci Rep. 2018;8(1):13804.
A New Cardiac Channelopathy: From Clinical Phenotypes to Molecular Mechanisms Associated With Na1.5 Gating Pores. Front Cardiovasc Med. 2018;5:139.
Biophysical, Molecular, and Pharmacological Characterization of Voltage-Dependent Sodium Channels From Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Can J Cardiol. 2017;33(2):269-278.
Induced pluripotent stem-cell-derived cardiomyocytes: cardiac applications, opportunities, and challenges. Can J Physiol Pharmacol. 2017;95(10):1108-1116.
Biophysical characterization of the honeybee DSC1 orthologue reveals a novel voltage-dependent Ca2+ channel subfamily: CaV4. J Gen Physiol. 2016;148(2):133-45.
Gating pore currents, a new pathological mechanism underlying cardiac arrhythmias associated with dilated cardiomyopathy. Channels (Austin). 2015;9(3):139-44.
Characterization of the honeybee AmNaV1 channel and tools to assess the toxicity of insecticides. Sci Rep. 2015;5:12475.
Gating pore currents are defects in common with two Nav1.5 mutations in patients with mixed arrhythmias and dilated cardiomyopathy. J Gen Physiol. 2015;145(2):93-106.
[Omega pore, an alternative ion channel permeation pathway involved in the development of several channelopathies]. Med Sci (Paris). 2015;31(8-9):735-41.
Biophysics, pathophysiology, and pharmacology of ion channel gating pores. Front Pharmacol. 2014;5:53.
Nav 1.5 mutations linked to dilated cardiomyopathy phenotypes: Is the gating pore current the missing link? Channels (Austin). 2014;8(1):90-4.
Molecular biology and biophysical properties of ion channel gating pores. Q Rev Biophys. 2014;47(4):364-88.
Novel SCN5A mutations in two families with "Brugada-like" ST elevation in the inferior leads and conduction disturbances. J Interv Card Electrophysiol. 2013;37(2):131-40.
Sodium overload due to a persistent current that attenuates the arrhythmogenic potential of a novel LQT3 mutation. Front Pharmacol. 2013;4:126.
Mexiletine differentially restores the trafficking defects caused by two brugada syndrome mutations. Front Pharmacol. 2012;3:62.
Gating pore currents and the resting state of Nav1.4 voltage sensor domains. Proc Natl Acad Sci USA. 2012;109(47):19250-5.